Brain cancer
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Researchers have found that a drug used to treat the symptoms of Parkinson’s disease may be effective at treating metastatic breast cancer and the brain metastases that can often result. The repurposed drug could be a novel cancer treatment.
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Researchers have discovered how a metabolite involved in repairing damaged DNA not only controls a person’s sensitivity to cancer therapies but can also protect healthy tissues from damage. The findings may lead to more effective cancer treatments.
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Researchers have created the world’s first biobank of living tissue collected from patients with metastatic brain cancer, providing a means of research and drug testing, with the data collected available to the international scientific community.
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Researchers have discovered that cerebrospinal fluid, the brain's shock absorber, may cause treatment resistance in people with brain cancer. But they identified a sixty-year-old drug that can be repurposed to resensitize cancer cells to treatment.
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Researchers at Harvard Medical School have developed a new AI-powered tool to help brain surgeons combat cancer. CHARM rapidly evaluates tumorous tissue during surgery to help professionals make on-the-spot decisions about how to proceed.
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Researchers have used nanowires to ‘catch-and-release’ DNA in urine, enabling them to detect mutations that signify the presence of a brain tumor. Their method may one day mean that invasive tissue biopsies are no longer required.
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The blood-brain barrier performs a vital function in keeping out toxins and pathogens, but it can become “leaky.” Now Stanford scientists have identified therapeutic molecules that could help patch it up, to potentially prevent neurological diseases.
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A new study has found that combining radiotherapy with a cancer-targeting virus was more effective at combatting a hard-to-treat, deadly form of brain tumor than using either therapy alone. The finding may lead to more effective cancer treatments.
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Researchers tricked glioblastoma cancer cells in mice into taking up iron-filled carbon nanotubes. They then shredded those cells by spinning the tubes using magnetic force. The technique has the researchers hopeful for a similar result in humans.
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In new hope for aggressive brain cancers, injecting a drug-laden hydrogel into the brain after tumors were surgically removed was found to launch a combined chemo- and immunotherapy attack, preventing cancer from returning in 100% of treated mice.
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By removing certain amino acids from the diets fed to rodents suffering from glioblastoma, researchers found that brain cancer cells began dying. What's more, mice put on the restrictive diets were also more receptive to chemotherapy treatment.
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Scientists have found a way to fight cancer with cancer, by genetically engineering cancer cells to release drugs at established tumor sites and stimulating the immune system. Tests in mice showed promise as both a therapy and preventative vaccine.
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