What's the equivalent amount for an average human when compared to 2 tablespoons a day for a rat?

A regular mouse weighs anywhere from 30g to 90g. A teaspoon of canola oil is about 4g so two teaspoons is 8g. So assuming at the higher end of the scale, that's like eating about 10% of your body weight in canola oil each day (I weigh 190 lbs so that would be 19 lbs of canola oil per day). That seems extraordinarily high except mice eat about 15g of food per 100g of body weight per day, so if you had an 80g mouse it would eat about 12g of food. So if 8g is canola oil then it presumably eats 4g of other food. Another interesting thing is that canola is about 8.8 calories per g, so 8g has about 70 calories. No wonder the mouse is getting fat? (If I ate 15% of my body weight per day that would amount to 28.5 lbs of food per day - I don't do this).

Firstly, the study was with mice, not even routes. According to this site, a mouse needs around 160kCal per day. And adult human would generally need 10 times that. Just using that value of 10x, 2 tblspoons for a mouse would be like 20 for a human. That's about 600mls of oil or an entire pint! At 8 calories/ml that would also be 4800kCal. Um, yeah, I think that would cause all sorts of problems, weight gain obviously (as per the study). I'm not sure one could single out the fact the oil was Canolo oil as being the problem them! I'd take this study with a grain of canola oil.

I fully agree with Grunchy. Despite we use canola oil as lubricant for chain saw and biodiesel only.

Mice that are engineered to get Alzheimers. Massive amounts of fats. A academic environment where researchers must publish exciting data. What could possibly be wrong there?
Universities are now our new religion.

Per body mass of a mouse, one drop per day is an overload compared to human consumption.

Another fine example of 'scientific' study gone horribly wrong. As others have mentioned...wait a minute, you made them fat, and that is the fault specifically of Canola Oil??? Hold ON! Now, if they also tried other oils, and these ALSO made the mice fat, but did not cause AD, then sure, its still a valid experiment. Now reading further, YES, they tested mice with EVOO, so I went and read that paper....wherein they CONTROLLED the diet to prevent the mice from gaining weight in the EVOO rich group (I'm sure they did not get anywhere near 2 tsp.)...which means they cannot compare the two studies... What a load of ____. If they really want to say canola oil is worse than other oils, they need to do the experiment EXACTLY the same for multiple types of oil, otherwise all that can be said is that eating ~1lb of pure oil a day will lead you to AD!

Two table spoons to a mouse is like half a bath full to a human, its a wonder they didnt just drown in it.

I'd like to see a study where one group gets Canola oil and the control group gets some other oil - say Olive oil. What this study established, to me, is that eating a bunch of oil, of any kind, would exacerbate Alzheimer's. Yet Canola gets a bad rap.

Canola oil is one of the main culprits in processed food, moving the omega 6/ omega 3 ratio toward omega 6.