Placebo effect possibly? I just don't see any amount of melatonin being absorbed through the skin as being therapeutically possible. Unless attached molecularly via a carrier such as DMSO or some other method, I'm a little leery of just a couple milligrams sprayed dermally as being enough to reach the brain stem area, much less making the trip easily since the skin also acts as a filter mechanism as well as a fluid transferal processor. And I'm just a layman saying this. I'd have to see some real facts before believing in homeopathic mumbo-jumbo. I've swam in the ocean yet didn't come out brined!

Very impressive!

I need a gallon PLEASE ! I hope it works, that would be soooo Cool.

If this works , I want it!

Many drugs are administered transdermally via skin patches. Several pain meds only dose in the micrograms per hour yet are as strong as taking a handful of hydrocodone pills several times throughout the day. Also the birth control patch which is a set of hormones, and the smoking cessation patch of nicotine.

I'd like to know where they got their 0.03 mg dosage recommendation. The MIT study cited by other sources says the recommended dose is 0.3mg. They also seem to give contradictory information. They claim the liver inactivates 90% of oral melatonin. So then tablets with 10x the recommended dose would seem to be the obvious solution, since 1/10 times 10 = 1.
This is ridiculously expensive at $15 for 30 doses. You can buy 100 timed release 300 mcg (0.3mg) tablets for the same price.

Pills are far cheaper to manufacture than aerosol sprays. You pay for the convenience.

Melatonin is addictive and causes your body to stop producing as much should you stop using it so after you don't use it you will need a many days to start producing normally again. Also your tolerance builds up so you will need more and more.
From experience.

Melatonin is a natural hormone so is not addictive, anymore than L-tyrosine or testosterone.
If you are low on melatonin, you will have trouble falling asleep.
If melatonin is not helping you get to sleep, then the problem is something else.

Adictive is a different issue. Given a supply that the body says is enough, the body mechanisms will throttle back your own production od melatonin, and there will be a "habituation" to the external supply, and a period of reseting natural production after cesation of the spray. the 90% destroyed in the stomach means 10%, which is what is in the spray, is the proper dose. (10% of the stomach dose)
note they had to go to a non mfg to get this up? they had to go to the gulible funding sources...