Drug
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A phase 3 clinical trial has shown that a drug called teplizumab can slow progression of type 1 diabetes in children and teenagers with a recent diagnosis. The trial’s success helps expand options for patients and relieve some burdens of the disease.
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A phase 3 clinical trial of tirzepatide, sold as Mounjaro, has demonstrated that if taken after an initial weight loss brought about by diet and lifestyle changes, the drug can lead to significant additional weight reduction.
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An existing blood cancer drug has been used to eliminate dormant HIV-infected cells that can cause the infection to reactivate when suppressive antiretroviral treatment is interrupted. The drug could remove the current need for lifelong medication.
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Researchers have developed the world’s first oral drug to target a form of cholesterol that has previously been untreatable and is largely caused by genetics, making it difficult to control by way of exercise, diet or other lifestyle factors.
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The US Food and Drug Administration recently fast-tracked its approval of brexpiprazole (Rexulti), an antipsychotic for treating agitation in dementia patients, when clinical studies demonstrated an increased risk of death and no meaningful benefit.
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Researchers have developed a drug that targets a protein essential for the growth and survival of cancer cells. The pill was found to be effective in preclinical studies and is now the subject of human clinical trials.
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Clinical trials of a novel non-opioid analgesic have found it to be effective in reducing acute postoperative pain, opening the door to a new way of managing short-term pain that avoids the pitfalls associated with using opioids.
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We’re losing the arms race against bacteria as they increasingly develop resistance to our best drugs. Now scientists have identified a new class of molecules that disable a major superbug weapon, which could make existing antibiotics effective again.
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Paracetamol and ibuprofen are among the world’s most common painkillers, but manufacturing them requires crude oil. Now, researchers have developed a more sustainable method, creating the drugs out of waste products from the paper industry.
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A gene called MYC is implicated in the majority of cancers, but unfortunately it’s often considered “undruggable.” In a new study scientists have developed a molecule that chops up the RNA of this gene, effectively clearing cancer in mice.
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A Phase 3 clinical trial of the drug donanemab has shown it can significantly slow cognitive and functional decline in people with early-stage Alzheimer’s disease, compared with existing treatments.
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Melbourne’s Monash University has commenced a Phase 1 clinical trial to test a novel inhaled powder designed to prevent postpartum hemorrhage, a serious complication of childbirth that causes tens of thousands of deaths worldwide.
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