Immunotherapy
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Aspirin, taken by around 29 million Americans daily, has increasingly been linked to inhibiting the growth of certain cancers – but we didn't quite know how. Now, scientists have uncovered how it helps the immune system see and kill cancer cells.
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Giving infliximab, an immunotherapy drug, as soon as possible after diagnosis with Crohn’s disease significantly reduced complications, including the need for urgent surgery by a factor of 10, a clinical study has found.
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A new form of immunotherapy helps immune cells “armor” themselves against exhaustion by releasing their own medicine to keep them going in the fight against cancer. The new method is faster and cheaper to produce than existing immunotherapies.
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Researchers have found adding a hyperactive form of the protein Rac2 to macrophages, immune cells that eat pathogens, causes them to cannibalize T cells. The novel technique could potentially boost the effectiveness of an emerging cancer treatment.
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Researchers have harnessed the cancer-destroying abilities of the body’s natural killer cells. Nanodrones selectively target a tumor, enabling the killer cells suppress cancer growth, opening the door to novel, cancer-specific immunotherapies.
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Moderna has announced results of a Phase 2b trial of its mRNA treatment for skin cancer. When paired with immunotherapy, the treatment significantly reduced risks of recurrence, metastasis and death, paving the way for trials against other cancers.
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In what has already been tagged as a “game-changer” for cancer treatment, the potent once-a-day tablet known as divarasib has continued to impress at Phase 1b trial stage, outperforming not just current therapies but its previous trial results.
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A study has found that a fatty acid found in meat and dairy may boost the cancer-killing abilities of the immune system’s T cells. Also found to enhance the effectiveness of immunotherapy, the nutrient could be used to complement cancer treatments.
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A Phase 2 clinical trial of immunotherapy drug tarlatamab, produced promising results in patients with small cell lung cancer, a particularly aggressive form of cancer, for whom previous treatments haven't worked.
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Researchers have developed a liquid gel that solidifies when injected into a solid tumor, is visible on a CT scan, and can slow-release cancer-fighting treatments. Combining the gel with immunotherapy improved survival in treatment-resistant cancers.
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Immunotherapy is a promising cancer treatment, but it can take too long. In a new study, scientists have taken steps towards an “off-the-shelf” therapy that could be mass produced and quickly rolled out to patients with a variety of cancer types.
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Cancer vaccines are a medical holy grail – but what if you could repurpose a vaccine you’ve already had? Scientists have demonstrated in mice a way to trick the immune system into attacking tumors by mistaking them for a pathogen it already targets.
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