Vaccines
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The biggest tragedy of pet ownership is that they just don’t live long enough. Thankfully scientists are working on that, with a new cancer vaccine for dogs that almost doubles their survival rates in the face of certain types of the disease.
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A man that police caught taking 217 doses of COVID vaccine has offered himself up to researchers for a study looking into what happens to the immune system after so many doses. The results offer surprising insight into these new mRNA vaccines.
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Researchers found that getting a multidose vaccine in different arms may improve the body’s immune response to the vaccine by up to four-fold. While they exclusively looked at the COVID-19 vaccine, they suspect this effect may be seen with others.
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Using a virus-mimicking DNA scaffold instead of the usual protein one to deliver a vaccine to mice not only generated a robust immune response but avoided the off-target effects sometimes seen when proteins are used.
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In regions where dogs often run loose, don't wear tags and aren't chipped, it can be hard for authorities to keep track of which ones have been vaccinated against rabies. A new app could help, by identifying dogs via facial recognition technology.
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The first study of its kind has looked at every UK resident – more than 67 million people – across four months, and found that, as vaccine uptake tapered off in 2022, 7,180 hospitalizations and deaths could have been avoided had jabs been up to date.
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Researchers have developed a novel intranasal COVID-19 vaccine that enhances the immune system’s response to the virus, providing longer-lasting, greater protection than vaccine injections, even against new and emerging variants.
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Researchers have developed a powdered vaccine that's inhaled directly into the lungs for an effective immune response. The vaccine can deliver multiple antigens, meaning one dose could provide broad-spectrum protection against several respiratory viruses.
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Researchers discovered that a modification to the synthetic mRNA used in therapeutics can cause the cell’s machinery to misread its instructions, leading to unintended immune responses. Importantly, they’ve also discovered a solution to the problem.
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Cancer vaccines are a medical holy grail – but what if you could repurpose a vaccine you’ve already had? Scientists have demonstrated in mice a way to trick the immune system into attacking tumors by mistaking them for a pathogen it already targets.
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Hospital patients often pick up dangerous, hard to treat infections. An experimental vaccine given on arrival to hospital could protect against a range of drug-resistant bacteria and fungi, by activating a different arm of the immune system.
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Sure, parts of the world are understandably feeling a bit of vaccine fatigue. But we're not too far off the first combination mRNA jab, which aims to offer seasonal protection against COVID-19 and influenza. Moderna hopes to be first out of the blocks.
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