Alzheimer's Disease

Harmful clusters of certain proteins are seen as key players in the cognitive decline associated with Alzheimer's disease, and scientists have now found that a novel gene therapy may be able to prevent a significant portion of them from forming.

Two studies are offering new evidence the microbiome is intertwined with our metabolic and brain health. One shows a link between gut bacteria and cognitive changes in a mouse model of Alzheimer’s, while another suggests microbial biomarkers could predict the progression of diabetes.

A new study has demonstrated how the brain's waste disposal system might be kicked into gear via ultrasound to treat Alzheimer's, with the technique proving effective in stimulating activity of this system in patients as part of early human trials.

Given the difficulty in diagnosing the Alzheimer's, scientists are exploring all kinds of avenues to reveal the disease in its early stages. New research indicates a person's pain perception could be used a biomarker for diagnosing Alzheimer's.

Scientists have studied the brains of a group of elderly individuals with excellent memory known as SuperAgers, and found them to be far more resistant to the troublesome buildup of proteins associated with Alzheimer's disease.

A new study has demonstrated how differences in walking patterns might help in distinguishing Alzheimer’s disease from other types of dementia, by focusing on one specific aspect of the patient’s gait.

A new study is suggesting heart disease in mid-life is linked to cognitive decline in senior years. The research found subjects in their 50s with mild hypertension displayed evidence of impaired brain metabolism in areas associated with Alzheimer’s.

Researchers have shed new light on the murky origins of neurodegenerative diseases like Alzheimer’s, which could eventually lead to new treatments. The team uncovered a mechanism for how toxic tangles of tau proteins leak into healthy brain cells.

A new observational study is building on a body of data finding a correlation between afternoon naps and improved mental agility. The research hypothesizes afternoon naps may help moderate age-related neuroinflammation helping keep the brain healthy.

Although yet to be published in a peer-reviewed journal, pharmaceutical company Eli Lilly has announced promising results from one of its Phase 2 human trials testing an experimental Alzheimer’s disease drug designed to slow cognitive decline.

A robust new study has comprehensively demonstrated how SARS-CoV-2, the coronavirus that causes COVID-19, can infect the brain and central nervous system. The study validates a growing body of research attributing neurological issues to COVID-19.

A new study has identified three different molecular subtypes of Alzheimer's disease. The research suggests these subtypes are so distinct from one another they could account for previous clinical trial failures and inconsistent translational studies.