Alzheimer's Disease
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Scientists have, for the first time, identified five distinct subtypes of Alzheimer’s disease, each with different neurodegenerative behaviors, survival rates and medical interventions. It could be a game-changer for research and therapeutic success.
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In 2023, researchers homed in on a variety of relatively small and simple lifestyle modifications that can positively impact human health. These are discoveries you can use right now to potentially boost your health, fight disease, and live longer.
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A study has found that, for older adults living alone, owning a pet was linked to slower rates of decline in some aspects of cognition and may completely offset the association between living alone, a recognized dementia risk, and cognitive decline.
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A study has found that treatment with a ‘chemical chaperone’ reduced the accumulation of protein plaques and restored cognitive functioning in mouse models of Alzheimer’s, which could lead to novel treatments to help treat the debilitating disease.
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Scientists have solved the mystery of which protein triggers the onset of many cases of frontotemporal dementia, paving the way for more effective early diagnosis of the degenerative disease and the development of potentially life-changing treatment.
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Research has found that non-invasively applying a mild electrical current to the brain twice a day for six weeks improved cognitive functioning and plasticity, the ability of the brain to ‘rewire’ itself, in patients with Alzheimer’s disease.
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Research has found that some personality traits increase the risk of a dementia diagnosis, whereas others reduce it. The findings suggest that targeting these traits earlier in life may be a way of reducing dementia risk in the long term.
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Research has revealed how genetic changes in a specialized population of brain cells called microglia contribute to neuroinflammation and, in turn, to Alzheimer’s disease. The findings could lead to more effective, targeted therapeutics.
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Caffeic acid, derived from coffee grounds, could help shield the brain from developing diseases such as Alzheimer's and Parkinson's. With six million tons of grounds dumped each year, this could be the most valuable 'upcycling' of the by-product yet.
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In a significant development for brain health, scientists have found that hemorrhages can occur due to a faulty interaction between aged red blood cells and narrow capillaries. Injured or damaged blood vessels were thought to be the sole culprit.
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Analyzing the functional connectivity of different brain networks, researchers found that Alzheimer’s disease disrupts areas of the brain beyond those relating to memory and produces changes distinct from those seen in healthy aging.
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Because of the logistics and invasive procedures involved, many people put off getting tested for Alzheimer’s and Parkinson’s diseases. Thanks to a new device, however, such testing could soon be performed non-invasively at just about any location.
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