Antibiotic

Antibiotics may work, but they drive bacteria to evolve into new drug-resistant forms. Now a new study has uncovered a mechanism that could make the bugs non-infectious without killing them, reducing the evolutionary pressure that leads to superbugs.

Bacteria have a nasty ability to rapidly evolve, allowing them to evade antibiotics in short order. But now, scientists at UC San Diego have used evolution against them, by “training” bacteria-killing viruses to anticipate their next moves.

Antibiotic-resistant bacteria, or “superbugs,” pose one of the most dangerous looming threats to public health. Now, researchers have found a new potential weakness in some of the worst strains, which makes them choke on their own toxic molecules.

Microneedle patches already show a great deal of promise as a painless alternative to hypodermic needles. A new one, however, could find use as a more effective means of treating serious bacterial infections of the skin.

By turning modern scientific tools on an antibiotic discovered 70 years ago, researchers have unearthed a previously unknown mechanism it uses to pierce and pop superbugs like balloons, raising new hopes in the fight against drug-resistant bacteria.

Bacteria have developed crafty weapons in their ongoing wars, such as tailocins, which act somewhat like “homing missiles” against their enemies. Now, researchers have investigated just how tailocins work, and how we might use them to our advantage.

It may be a bit gross, but mucus plays a key role in our bodies. Now, an MIT team has managed to create an artificial version of the stuff, and shown that it’s an effective antimicrobial – even more so than real mucus.

Antibiotic-resistant bacteria are an urgent public health threat. A new single-dose drug has been developed that works on a different mechanism to most antibiotics, and tests in mice show that it can be used to treat multi-drug-resistant gonorrhea.

A study is offering clues to the origins of a deadly fungal pathogen that mysteriously appeared in hospitals around the world 10 years ago. The study chronicles the discovery of the pathogen for the first time in a remote natural environment.

Antibiotic-resistant “superbugs" pose a serious public health threat. New antibiotics are needed to turn the tide, but developing them takes time. Now IBM Research has set AI on the task, producing two promising new drug candidates very quickly.

New research led by scientists from UT Southwestern suggests a novel combination of three old antibiotics may be repurposed into an alternative to opiates for a particular kind of nerve pain.

Bacteria are fast evolving resistance to antibiotics, meaning our best drugs could soon stop working entirely. Now researchers have found a way to bypass drug resistance in these so-called superbugs – by distracting them with predatory viruses.