The FDA has granted accelerated approval to a new cancer drug called selinexor. This pill has been found to be successful in treating multiple myeloma in patients that hadn’t had success with other treatments. But at this very early stage the drug comes with some major caveats.
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Researchers at MIT have identified a surprising new dynamic drug duo to fight cancer, combining two classes that are already beginning to be widely used. Interestingly, the combo appears to work in a completely different way to what scientists previously expected.
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By guiding evolution, scientists have managed to manipulate micro-organisms into producing useful new drugs and materials, but it’s a time-consuming process. Now, UNC researchers have developed a new tool that speeds up the process in mammalian cells, creating new therapeutics in a matter of days.
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Researchers at the Technical University of Munich (TUM) have demonstrated a prototype of a drug that can release three active ingredients, at different times in sequence. The key to this unusual and useful ointment is artificial DNA, which breaks down at precise intervals.
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Humans are currently locked in an arms race against pathogenic bacteria – and we’re losing. Now scientists have identified the genes responsible for antibiotic resistance in a particularly dangerous superbug, and found a way to thwart them.
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Research led by the University of Arizona may have uncovered a new potential treatment target for tinnitus – not the ears but within the brain itself. The study suggests that neuroinflammation is to blame, and could be a new way to fix the problem.
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Antibiotic-resistant bacteria might also be one of the biggest medical issues of the 21st century. Now, a bacterial gene that grants resistance to “last resort” antibiotics has been detected in a patient in the US, for the first time.
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Researchers have uncovered a new weakness that could be exploited to produce new antiviral drugs. The team discovered a compound that can prevent certain classes of viruses from infecting cells, paving the way for new treatments against diseases like the common cold, meningitis or polio.
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As promising as some treatments are in lab tests, unfortunately they don’t always meet hopes when translated to the real world. Now scientists have found out why a class of cancer drugs failed in human trials, and gone on to identify another drug that could finally make the treatment work.
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It’s entirely possible that micro-machines could one day be delivering drugs inside the body, with many designs proposed in recent years. The latest comes from the University of New South Wales (UNSW), which gets around under its own power using a system similar to how submarines rise and sink.
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