Drug

A gene called MYC is implicated in the majority of cancers, but unfortunately it’s often considered “undruggable.” In a new study scientists have developed a molecule that chops up the RNA of this gene, effectively clearing cancer in mice.

A Phase 3 clinical trial of the drug donanemab has shown it can significantly slow cognitive and functional decline in people with early-stage Alzheimer’s disease, compared with existing treatments.

Melbourne’s Monash University has commenced a Phase 1 clinical trial to test a novel inhaled powder designed to prevent postpartum hemorrhage, a serious complication of childbirth that causes tens of thousands of deaths worldwide.

Missing medications or not taking them as required can have costly results. Bioengineers at Rice University may have the solution to missed medications, using advanced technology to create a system that delivers time-released drugs.

Heart failure is commonly complicated by sleep apnea, a co-morbidity that further reduces a person’s lifespan. A promising new drug could treat heart failure and sleep apnea by targeting the nervous activity that drives both.

Ovarian cancer is marked by low survival rates and a high rate of recurrence despite treatment. But a promising cancer-fighting drug is undergoing clinical trials, providing hope for women whose cancer has returned following chemotherapy.

Humans have bitter taste receptors not only in their mouths but in their lungs, too. Researchers have exploited these receptors’ innate ability to dilate the airways to create a potent new drug that may change how we treat diseases like asthma and COPD.

High cholesterol levels are a common and potentially deadly health problem, but a new drug could help more people manage the condition. An experimental pill has been shown to reduce levels of “bad” cholesterol by 60% in a phase 2 clinical trial.

There are plenty of studies into the effects of cannabis on health. But a first-of-its-kind US study has found a connection between different patterns of cannabis use by patients and how well they recover from surgery.

Male contraceptives have traditionally been limited to condoms and vasectomies. Now scientists have demonstrated a promising new method that takes the form of a pill that can be taken just before sex, greatly reducing fertility for 24 hours.

Scientists at MIT have developed bottlebrush-shaped molecules that can carry groups of different cancer drugs in just the right ratios. Tests in mice showed significantly improved outcomes compared to just giving the drugs loose.

In an ideal world, managing diabetes wouldn’t involve insulin injections but just popping a pill. Now a team of scientists has demonstrated an oral tablet that’s self-propelled by chemical “micromotors” to deliver insulin in the colon of rats.