Drug
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Amid ongoing global shortages of semaglutide, the active ingredient in medical sensations Ozempic and Wegovy, researchers have uncovered a way to make 10 times more of the stuff, producing a therapeutically similar version of the in-demand drug.
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A study has found that a compound created by the body’s breakdown of a cancer drug has therapeutic properties that could be used in combination with the original drug to boost prostate cancer treatment or as a novel treatment for Parkinson's disease.
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A series of Phase 3 clinical trials into a novel oral, non-opioid painkiller has found that it’s effective in treating acute pain in both surgical and non-surgical settings. The drug's manufacturers plan to seek FDA approval in mid-2024.
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White blood cell numbers can be cut by health conditions or treatments like chemotherapy. Yale scientists have now discovered a molecule that can be given to quickly boost their numbers back up, to help fight off infections without antibiotics.
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No matter how important something is, too much of anything is bad for you. Scientists have now put that principle to work to kill cancer, with a new drug that causes calcium to build up and choke the tumor to death.
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Researchers have created a ‘two-headed’ drug that prevents the production of the toxic protein linked to Parkinson’s disease before destroying the RNA machinery that makes it. The drug may be a way of slowing or even stopping the disease’s progression.
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Antibiotic-resistant bacteria are poised to become a global health concern. In the race to develop new weapons, scientists have created a new family of antibacterial polymers that can kill 'superbugs' in a way they can't evolve resistance to.
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An effective single-dose, long-term treatment for anxiety could be within reach, with the phase 2b clinical trial of MM-120 reported to have passed the stage with flying colors.
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A world-first clinical trial has found that a drug commonly prescribed for rheumatoid arthritis preserved the pancreatic cells’ ability to produce insulin and slowed the progression of type 1 diabetes in those recently diagnosed with the condition.
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Managing diabetes usually involves regular shots, but soon patients might only need injections a few times a year. Stanford has developed a hydrogel-based delivery system that slowly releases drugs over months to control diabetes and even weight.
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A clinical trial of a non-benzodiazepine drug, a version of a naturally occurring neurosteroid, has shown that it’s as effective as Xanax at reducing anxiety. Critical to the trial’s success was technology that converted the neurosteroid into oral form.
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People with high blood pressure may soon be able to swap the daily pills for an injection every few months. A phase 2 clinical trial has shown that Zilebesiran can drastically reduce blood pressure for long periods of time with no side effects.
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