Dana-Farber Cancer Institute

CAR T cell immunotherapy is a promising cancer treatment that supercharges natural tumor-hunting cells, but it can backfire with potentially deadly results. Now, scientists have engineered off switches for these immune cells.

Preliminary results from a small human trial testing a novel cancer drug revealed over half the cohort had their tumors stop growing completely. The drug, called berzosertib, is now moving to larger clinical trials.

Scientists at the Dana-Farber Cancer Institute have published a study describing a new type of blood test that can detect more than 20 types of cancer with a high degree of accuracy. Not only that, it can even trace them back to their source.

Scientists at the Dana-Farber Cancer Institute have developed a new approach to treating rheumatoid arthritis.

Researchers have discovered that a small molecule compound called JQ1 can produce reversible birth control in mice, thereby showing promise as a lead compound for the development of a reversible male contraceptive.

Researchers have confirmed the existence of a third type of fat cell, in addition to white and brown, that could be targeted in the fight against obesity.