Genetics
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Up to four million Americans may be enduring this common ailment right now. But what if a microbe found in the gut could relieve it and restore gut health? Scientists believe they've found the genetic key that powers this microbe's motility engines.
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They've lived on earth for 280 million years at least, but starfish – or sea stars – remain a huge mystery in biology. Now, long-held beliefs regarding their unique design have been upended, as genetics reveal they're not all arms but nearly all head.
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Researchers presented the interim results of a clinical trial using a single infusion of gene-editing technology to permanently switch off LDL cholesterol production in people with a genetic condition that elevates levels of the ‘bad’ cholesterol.
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A 15-year project trying to build a synthetic yeast genome has hit a major milestone – yeast cells with more than 50% synthetic DNA for the first time. The team created synthetic versions of almost all its chromosomes plus a completely new one.
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Researchers have conducted the first human trials of a new drug, lepodisiran, and found that a single injection reduced lipoprotein(a) – a ‘bad’ cholesterol with a genetic basis and no available treatments – to undetectable levels for almost a year.
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Researchers have identified the gene responsible for setting off a cellular chain reaction that causes prostate cancer to metastasize to the bone. The discovery could have significant implications for treating prostate and other cancers.
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In a fascinating new study, scientists have for the first time uncovered the heart-brain pathway, fueled by specific over-excited sensory neurons, that triggers fainting. The discovery is a huge step towards targeted treatments for a host of conditions.
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Lending new meaning to the phrase ‘cat burglar’, a single feline hair left at a crime scene can be traced back to an individual animal through a new method that can highlight a unique, rare genetic ‘fingerprint’. You could say it turns the cat into a rat.
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The way a sunflower bends to follow the Sun across the sky each day can be quite dramatic. Now, scientists have uncovered something equally dramatic: it does it through unique genetic transcription, which rewrites what we know about its special Sun dance.
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Researchers have identified a gene in golden retrievers associated with long life that’s related to a gene that causes cancer cells to grow quickly in humans. The discovery has the potential to help our furry besties and us.
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A new study has investigated the biological mechanisms brought about by calorie restriction and found that a moderate reduction in calorie intake can improve muscle health and activate biological pathways important for good health.
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Researchers have identified previously unknown genes linked to calcium buildup in the coronary arteries, a predictor of future heart disease. The discovery has the potential to provide new avenues for preventing coronary artery disease.
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