Materials

Large quantities of synthetic spider silk spun on demand

A new process developed by Swedish researchers using bacteria and spider silk proteins that mimics natural spinning production has provided the means to produce kilometer-long lengths of artificial web material
A new process developed by Swedish researchers using bacteria and spider silk proteins that mimics natural spinning production has provided the means to produce kilometer-long lengths of artificial web material
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Highly concentrated spider silk protein solution in a syringe is pumped through a pulled glass capillary with a tip size of 10-30 micrometers, with the tip submerged in a low pH aqueous collection bath
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Highly concentrated spider silk protein solution in a syringe is pumped through a pulled glass capillary with a tip size of 10-30 micrometers, with the tip submerged in a low pH aqueous collection bath
Picture of a fiber as it is spun in the low pH aqueous collection bath
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Picture of a fiber as it is spun in the low pH aqueous collection bath
A new process developed by Swedish researchers using bacteria and spider silk proteins that mimics natural spinning production has provided the means to produce kilometer-long lengths of artificial web material
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A new process developed by Swedish researchers using bacteria and spider silk proteins that mimics natural spinning production has provided the means to produce kilometer-long lengths of artificial web material
Artificial spider silk as spun and hung on frames
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Artificial spider silk as spun and hung on frames
Researchers Anna Rising and Jan Johansson
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Researchers Anna Rising and Jan Johansson

Spiders may be scary for some people, but the silk that they produce to weave their webs is very appealing to many scientists. Amazingly tough, yet lightweight, spider silk has been used in everything from biodegradable sutures to violin strings, and even has possible applications in electronics and gene therapy. Unfortunately, spiders individually produce only small amounts of silk and wrangling enough of them into spooling out commercial quantities is nigh on impossible. Now a new prototype process that mimics the natural spinning process has been created, using bacteria and spider silk proteins to create large quantities of artificial web threads on demand.

Normally stockpiled as a watery solution in the silk glands of a spider, silk is made up of a number of proteins that solidify when spun into a fiber outside the body of the arachnid. The pH gradient found in these silk glands also affects individual segments of the proteins they contain to ensure that the fiber is formed quickly and consistently in exactly the right place.

Researchers Anna Rising, Jan Johansson, and Marlene Andersson working at the Swedish University of Agricultural Sciences (SLU) and at Karolinska Institutet took advantage of this knowledge to help create an artificial spider silk protein in bacteria that can then be bred en masse to produce industrial quantities of web material.

Highly concentrated spider silk protein solution in a syringe is pumped through a pulled glass capillary with a tip size of 10-30 micrometers, with the tip submerged in a low pH aqueous collection bath
Highly concentrated spider silk protein solution in a syringe is pumped through a pulled glass capillary with a tip size of 10-30 micrometers, with the tip submerged in a low pH aqueous collection bath

After the artificial protein is exuded from the bacteria, the researchers use a simple biomimetic process (that is, one that mimics nature) to ape a spider silk gland spinning apparatus by using a syringe to pump it through a glass capillary extruder to produce kilometer-long fibers controlled by the manipulation of pH levels. Fibers for the artificial silk produced using this new method are around 40 micrometers in diameter.

"This is the first successful example of biomimetic spider silk spinning," said Anna Rising. "We have designed a process that recapitulates many of the complex molecular mechanisms of native silk spinning. In the future this may allow industrial production of artificial spider silk for biomaterial applications or for the manufacture of advanced textiles."

The results of this research were recently published in the Nature journal Chemical Biology

The short video below shows the silk being produced in the laboratory.

Source: SLU

Formation of artificial spider silk / Konstgjord spindeltråd bildas

4 comments
Mzungu_Mkubwa
Peter Parker is either going to be very happy to hear about this, or you'll be hearing from his lawyers regarding IP/patent violations. "Thwip!"
windykites
I saw this video on the web the other day.
Grunchy
I am TOTALLY going to buy a spider silk shirt. Maybe a tie too..
noteugene
So, I guess, new rope?