Genetics

A new gene therapy for Duchenne muscular dystrophy (DMD) has shown promise in not only slowing the progression of the disease but potentially even reversing the muscle damage, with human trials set to begin within two years.

Scientists have assembled the most complete woolly mammoth genome in 3D, thanks to an incredible “freeze-dried” specimen. With its DNA preserved in a glass-like state, chromosomes were found for the first time, and even gene expression patterns.

An amphibian has lived up to its name, swapping out its usual green coloring for bright blue, in the first-ever record of a magnificent tree frog with this appearance. It's stunned scientists, who know they're unlikely to see this again.

In pre-clinical trials, a small molecule effectively regrew neurons, reduced inflammation, and improved memory, speed, coordination, grip strength, and more. The finding could have a profound impact on aging and the diseases that accompany it.

Since Neanderthals' whole genome was sequenced, there’s been growing interest in how their genetics influences our health. New research has found that genetic variations derived from our ancient relatives are associated with an increased susceptibility to autism.

New research uncovering the DNA-damaging mechanism by which a mutated gene causes a rare, fatal disease may have repercussions for the treatment of many other diseases linked to aging, including heart disease, autoimmune disorders, and cancer.

Scientists have discovered the organism with the largest known genome. At 160 billion base pairs, it's 50 times bigger than the human genome, and the organism it’s describing is a tiny fern you wouldn’t even notice if you tripped over it on a hike.

The world's first human trial of a drug that can regenerate teeth will begin in a few months, less than a year on from news of its success in animals. This paves the way for the medicine to be commercially available as early as 2030.

The number of people carrying an inherited mutation that predisposes them to melanoma is seven-fold higher than previously thought, according to a new study. Medical practitioners are urged to consider cancer risk factors beyond sun exposure.

Medically, AI is helping us with everything from identifying abnormal heart rhythms before they happen to spotting skin cancer. But do we really need it to get involved with our genome? Protein-design company Profluent believes we do.

Analysis of Beethoven’s DNA has revealed that he had a low genetic predisposition for musical ability. The study highlights how making genetic predictions for individuals, including famous historical figures, can be fraught with danger.

Researchers have identified two genetic markers that may explain the link between eating red and processed meat and bowel cancer. Understanding the disease process and the genes underlying it can help develop better prevention strategies.