To investigate how gut bacteria can affect overall health, researchers at Harvard Medical School have deleted a single gene from one gut bacteria species and found that it alters the metabolism of the host, reducing their weight gain.
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A new research paper has again raised doubts over the safety and accuracy of the CRISPR-Cas9 gene editing technique. The study suggests that the gene editing process can cause extensive unforeseen and unpredictable alterations to DNA sequences outside of the intended targets.
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The CRISPR gene editing revolution is less than a decade old and scientists are still learning how best to deploy this ground-breaking technique. A team has recently discovered why the technique sometimes fails, uncovering a novel insight that will hopefully make future research more efficient.
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The way genes are expressed can be changed by environmental or lifestyle factors and these changes may be inherited from parents. A new study has found that male mice who spend time in cold environments may pass down this “experience” to their kids, in the form of higher levels of warming brown fat.
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In one of the first examples of gene-editing technology being effectively used to knock out the expression of a gene in non-human primates, researchers have lowered the blood cholesterol in monkeys by disabling a single gene in the liver.
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An intriguing new study has homed in on several specific genomic regions that seem to be associated with greater traits of social isolation and loneliness. The results suggest genetic traits associated with loneliness cross over with a susceptibility for bad cardiovascular health and depression.
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Researchers have identified a new gene that plays a fundamental role in regulating the production of pro-inflammatory proteins. It's hoped the discovery of this previously unknown genetic mechanism will offer scientists exciting new pathways to treat a variety of diseases, from cancer to diabetes.
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A remarkable new study has successfully used the CRISPR gene editing system to edit a specific gene in mice engineered to have fragile X syndrome, a disorder often related to autism. The single gene edit in the live mice resulted in significant improvements in repetitive and obsessive behaviors.
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A team of scientists from Stanford University School of Medicine has discovered a blood-based genetic biomarker that could predict how likely a person is to become ill when exposed to the flu virus.
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Antibiotics aren’t very picky, indiscriminately wiping out both good and bad bacteria and upsetting the balance of your microbiome. Now, researchers at Penn State have developed a new approach to make a drug that can single out a specific, opportunistic bacteria known as C. difficile.
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