Genetics

A new study has found young cancer survivors show high expression of a gene known to be an effective marker of aging. The researchers say this genetic biomarker could identify cancer survivors most at risk of later-life frailty due to their treatment.

Using a multi-modal approach to data analysis, scientists have identified a subtype of autism linked with a gene cluster known to affect neurodevelopment and lipid metabolism. It's suggested this subtype accounts for nearly seven percent of autism cases.

A new study is questioning whether Alzheimer’s treatments previously found to be ineffective in human trials should be re-examined, after the discovery of a specific gene that can inhibit a therapy’s efficacy is only present in 75 percent of people.

A new genomic study has homed in on exactly when and where modern penguins originated, suggesting the birds first appeared in Australian and New Zealand waters about 22 million years ago before later spreading south into the cooler Antarctic waters.

New research suggests violent or traumatic experiences in childhood can accelerate biological signs of aging. Early puberty, rapid cellular aging, and structural brain changes could all be linked to violent childhood trauma, but not poverty or neglect.

Researchers have, for the first time, successfully gene edited a cephalopod. Using CRISPR-Cas9 technology, the research breakthrough will now allow scientists to conduct novel investigations into medical, robotic, and materials innovations.

In April 2020, a bull calf named Cosmo was born to a team of scientists. This probably wouldn’t normally be news except that this particular bouncing baby boy had his genome edited as an embryo, to make him more likely to produce male offspring.

In a landmark new study, geneticists have completely sequenced the entire human X chromosome. Using a new technique that takes "ultra-long" reads of DNA sequences, the team revealed more than three million base pairs that were previously unmapped.

The CRISPR-Cas9 gene editing system is an extremely powerful tool, but off-target edits can have serious consequences. Now, researchers have found a mutation of the CRISPR enzyme that’s almost 100 times more precise than the most commonly used one.

An archaeological conundrum may have been solved by DNA analyses carried out by a team of Stanford Medicine scientists led by Alexander Ioannidis that indicates Native Americans and Polynesians came into contact centuries before the arrival of the first Europeans.

A study from scientists at the University of California, Davis, has found unpasteurized milk, commonly known as raw milk, holds large volumes of antimicrobial-resistant genes which can swiftly spawn dangerous bacteria when left at room temperature.

While much research has investigated short-term physiological responses to exercise a new study has set out to examine how long-term physical training, consistently performed for over a decade, can influence gene activity to prevent metabolic disease.