Lifespan

Metolazone, an anti-hypertension drug, has been found to kickstart a lifespan-extending cellular repair process in roundworms. The mechanism may be translatable to humans, offering new research pathways in the search for an anti-aging drug.

A new study has compared the physical and cognitive performance of a group of older people in 2017 with a similarly aged group three decades earlier. Improvements were seen in almost every test, suggesting progress has been made extending healthspan.

A new study has found mice given supplements of an endogenous metabolite display significant healthspan improvements. The research follows on from other animal studies with the same compound and a clinical trial in middle-aged humans is getting underway.

A meta-analysis suggests naps lasting more than 60 minutes can be linked to higher rates of all-cause mortality and poor cardiovascular health. Although the finding is only correlational, the researchers suggest keep your siestas to less than one hour.

A new study is providing insights into a cellular energy pathway linked to longer lifespan. The research, conducted in human cells and roundworms, raises the prospect of anti-aging therapeutics that can extend lifespan by activating this pathway.

Hot on the heels of a recently published genomic study correlating blood iron levels with healthy aging, more research is suggesting high systemic iron levels can be linked with reduced life expectancy.

A large gene study has discovered several genomic regions linked to longer and healthier lives are also involved in metabolizing iron in the blood. The research suggests abnormal blood iron levels may fundamentally underpin many age-related diseases.

New research suggests a person’s lifespan could be predicted at a young age by measuring the volume of genetic mutations they accumulate, raising the prospect of developing medical interventions so people could live and stay healthy much longer.

It's already a well-known fact that on average, women live longer than men. A European study now indicates that the difference between male and female lifespans is even more pronounced in other types of mammals.

A large study out of China has found drinking green tea at least three times a week can be linked to longer lifespan and lower rates of heart disease and stroke. The same association was not seen in black tea drinkers.

Finding ways to slow down aging would help reduce all kinds of diseases. And now scientists have made a pretty substantial breakthrough, extending the lifespan of worms by a staggering 500 percent by tweaking a couple of cellular pathways.

Gauging the maximum lifespan of wild animals can be difficult, as scientists are limited to examining whichever creatures they capture. Now, however, researchers have developed a method of determining a species' natural lifespan, based on its DNA.