Max Delbrück Center for Molecular Medicine

A new study has pinpointed how the APOE4 gene variant sabotages the brain’s energy balance, blocking neurons from burning fat for fuel when glucose runs low, a discovery that could reveal new ways to prevent or slow Alzheimer’s disease.

As important as CRISPR-Cas9 gene-editing is, it has a relatively high error rate, which can introduce potentially harmful mutations. German researchers have now developed a more refined tool that reduces errors by nicking DNA instead of cutting it.

A new study is offering novel insights into the effects of too much salt on certain immune cells. The research reveals how salt can dampen mitochondrial functions, disrupting normal immune cell activity and potentially promoting inflammation.

Scientists are unraveling the mechanisms behind obesity piece by piece, with the latest example coming from researchers in Germany who have identified a protein that appears to play a "key role" in human fat metabolism.