Weight Loss

A new class of weight-loss drug has shown it can significantly boost weight loss when paired with GLP-1 therapy – without adding side effects – in a mid-stage clinical trial, pointing to a powerful new combination approach to tackling obesity.

In a world where slimness is often equated with health, a new Danish study has flipped the narrative: being slightly overweight, or even mildly obese, may not be as deadly as once thought. In fact, in some ways it could be safer than being thin.

A headline-grabbing study on apple cider vinegar has been pulled from the record, striking a blow to the science and wellness worlds. The research, which claimed that the tonic triggered massive weight loss, was found to be riddled with errors.

While Ozempic and other drugs like it have proven effective in helping people lose weight, many gain it back when the injections stop. A new drug targets weight loss differently, leading to a more permanent fat-shedding solution.

Scientists have found out exactly how an exercise-triggered molecule suppresses hunger signals in the brain, leading to weight loss. It could be harnessed as a therapeutic, providing the same benefit without the work it takes to produce it naturally.

Healthy eating doesn’t just shrink your waistline; it can ease chronic pain. A new study shows that better diet quality reduced pain severity and improved quality of life, independent of weight loss.

When scientists study obesity, it's often focused on genetics, physical activity and poor eating habits. However, new findings show that stress, hardship, isolation and social inequality create the biological environment that underpins the epidemic.

Large weight swings or weight loss in later life aren’t just physical health risks, they’re tied to fast memory and cognitive decline, a new study has found. It underscores the importance of weight stability for brain health in older adults.

Plant-based microbeads made from everyday ingredients like green tea and seaweed have helped mice shed weight by trapping fats in the gut. Researchers see these microbeads as a potential “structured, drug-free therapy” to treat obesity.

Researchers have successfully tweaked a specialized compound from brown seaweed to unlock its powerful anti-obesity potential. Instead of appetite suppression and fat burning, this molecule reshapes the gut microbiome to fight weight gain naturally.

It looks like we'll see oral GLP-1 drugs on the market by 2026, with Eli Lilly reporting impressive results from a large, robust 72-week trial that saw obese patients lose an average of 27.3 lb, or 12.4% of their body weight, with a once-daily pill.

The first human-tested weight-loss drug that burns calories through creatine-based heat generation, without reducing appetite, has successfully completed its Phase I trial. In the trial, participants lost an average of 3% fat mass in two weeks.