anti-aging

Alkahest, a California-based start-up, has just revealed some compelling early results from an ongoing Phase 2 trial into the efficacy of its novel formulation of plasma proteins derived from young blood, developed to slow, or even stop, the cognitive decline associated with Alzheimer’s disease.

​There is no shortage of scientists toiling away in the field of anti-aging. This line of inquiry has turned up yet another interesting discovery, this time demonstrating how a certain chemical compound works to keep cells active and young.

Researchers at EPFL have now reported a new step towards anti-aging medication. Human clinical trials of a fruit-derived compound showed promise in slowing mitochondrial aging in elderly patients, with no side effects found.

A new study is offering a new hypothesis to explain the long-standing idea that transfusions of young blood can reverse the effects of aging. The study reveals when older mice are supplemented with a protein taken from the blood of young mice, they live longer and exhibit youthful characteristics.

In a stunning piece of research, Stanford neuroscientists have hunted down a single gene that encodes a protein responsible for age-related cognitive losses, targeted it with special blocking antibodies, and shown in mice that these antibodies can rejuvenate old brains to work as well as young ones.

Given the chance, very few of us wouldn’t want to slow down the aging process. Chasing that fountain of youth is a major branch of medical science at the moment, and now, a team at Scripps Research has found that blocking a particular enzyme can extend the lifespan of worms by almost half again.

A team of genetic scientists at the Salk Institute have developed a new therapy using the CRISPR/Cas9 tool that takes a toxic protein out of the aging equation, with some promising results. ​

Ambrosia, the controversial medical startup selling transfusions of youthful blood under the premise it confers anti-aging benefits, has swiftly ceased operations hours after the FDA issued an oblique statement suggesting the treatment has not been proven to be safe or effective.

Researchers at the University of Michigan may have found a way to slow aging – in worms at least. The team has identified a molecule in neurons that, when blocked, improves motor function in older worms and increases their lifespan and general health. Similar pathways might be at work in humans too.

​A study has revealed a new anti-aging strategy designed to help the immune system remove old and dysfunctional cells from the body. The initial animal experiments restored youthful characteristics in old mice, suggesting improving immune system surveillance may be an effective anti-aging therapy.​

New research has found that endurance exercise, such as running, swimming or cycling, and high intensity interval training (HIIT)​ has the ability to not only slow, but actually reverse cellular aging, whereas resistance exercise, like pumping iron, does not.

Exciting research is highlighting a new subclass of anti-aging compounds hoped to extend lifespan, reduce the markers of aging, and slow the onset of diseases such as Alzheimer’s. The work is on the cusp of starting 2 human clinical trials investigating compounds derived from natural sources.