anti-aging

The most detailed genomic study ever conducted of individuals over the age of 100 years has homed in on several genetic traits that may protect from age-related disease. Gene variants improving DNA repair processes were particularly prominent.

A new study describes one way immune cells become dysfunctional as we age, leading to the inflammatory hyperdrive that plays a role in most age-related disease from cancer to cognitive decline, and suggests this immune dysfunction can be reversed.

Metolazone, an anti-hypertension drug, has been found to kickstart a lifespan-extending cellular repair process in roundworms. The mechanism may be translatable to humans, offering new research pathways in the search for an anti-aging drug.

Using gene therapy, Harvard scientists have restored vision to mice suffering glaucoma by rewinding the aging process in their cells. The team says the research is a proof of concept for slowing the symptoms of aging with epigenetics.

It’s long been thought that our cells stop dividing as we age as a natural preventative measure against cancer. Now a new study has found intriguing evidence supporting this hypothesis in genomes from several particularly cancer-prone families.

A new study led by the University of Edinburgh has identified a protein that plays a crucial role in protecting the body’s blood stem cells from damage during infection, a finding that could lead to new ways to slow down the aging process.

New research has shown how diluting the blood plasma of older mice can have strong rejuvenation effect on tissues and organs, by reducing the concentration of inflammatory proteins that typically increase with age.

Stanford scientists may have found a way to essentially return older cells to a more youthful state. The adult cells are treated with a mix of proteins from early embryonic development, which removes many of the molecular signs of aging.

Finding ways to slow down aging would help reduce all kinds of diseases. And now scientists have made a pretty substantial breakthrough, extending the lifespan of worms by a staggering 500 percent by tweaking a couple of cellular pathways.

Researchers have extend the lifespan of fruit flies by 48 percent using a triple drug combination made up of drugs already used in people.

Alkahest, a California-based start-up, has just revealed some compelling early results from an ongoing Phase 2 trial into the efficacy of its novel formulation of plasma proteins derived from young blood, developed to slow, or even stop, the cognitive decline associated with Alzheimer’s disease.

​There is no shortage of scientists toiling away in the field of anti-aging. This line of inquiry has turned up yet another interesting discovery, this time demonstrating how a certain chemical compound works to keep cells active and young.