Bioprinting

The distant scientific objective of 3D printed human organs has now grown a little bit closer, with researchers at Carnegie Mellon University reporting a breakthrough that enabled the printing of full-scale heart components that in some cases functioned similarly to the real thing.

Space travel is conducive to injuries. Now researchers from Dresden Technical University (TUD) have developed a 3D bioprinting method for use in space, creating new skin and bone tissue out of resources that might be available to astronauts.

Although it may be hard to believe that there is already an "established" method of doing something such as 3D-printing biological tissue, there does indeed seem to be one. It utilizes microscale scaffolds – which a newly-developed technique does away with the need for.

3D printing organs is going through some teething issues. Now researchers have found a surprisingly simple answer to the complex problem of printing detailed vascular networks, and shown it off with a dramatic model of a breathing lung that passes oxygen into surrounding blood vessels.

In an effort to scale up the manufacture of biomaterials, researchers at UC Berkeley have combined bioprinting, a robotic arm, and flash freezing that may one day allow living tissue and even whole organs to be printed on demand.

To help patch up large wounds that might normally require a skin graft, researchers at Wake Forest Institute for Regenerative Medicine (WFIRM) have developed a new bioprinter that can print dual layers of a patient’s own skin directly into a wound.

​Four years ago, we heard how researchers had created a microwave-oven-sized 3D printer that could produce sheets of skin for treating burns. Now, some of the same scientists have developed a handheld device that prints skin directly onto deep wounds.

​​A root canal can be a lifesaver for an infected tooth, but the process does involve cutting off the blood supply. Scientists have now come up with a way to fabricate new blood vessels in teeth, which may help them to regain important functionality. ​

We recently reported on heart structures 3D-printed in a weightless environment. For the first of a regular new feature, we asked one of the company’s chief scientist what was the single biggest impediment to having lab-grown organs available right now. Here’s what he had to say.

Recently, aboard a plane simulating weightlessness, a 3D bioprinter spit out heart and vascular structures created with human stem cells as part of a project that could one day lead to better and more plentiful human organs.​

Researchers have taken a sizeable stride towards future of 3D-printed tissue, working with a newly-developed machine to produce human-scale muscle structures that matured into functional tissue after being implanted into animals. ​​

As part of its ongoing effort to eschew animal testing, L'Oréal has teamed up with bioprinting company Organovo to develop 3D-printed skin tissue for testing of its products.