Broad Institute

Scientists have uncovered how an anti-cancer molecule works

Medical

Solving a molecular mystery may have opened new class of cancer drugs

Researchers at the Broad Institute have solved a molecular mystery that might lead to new treatments for cancer. The team has uncovered just how a strange molecule works to kill cancer by inducing a little-known type of cell death.

Harvard and MIT researchers have developed a new CRISPR gene-editing system called prime editing

Medical

Next-gen CRISPR system allows precise search-and-replace gene editing

CRISPR is a powerful gene-editing tool – but it has its own problems too. Now, Harvard and MIT scientists have created a new approach called prime editing, which could correct almost 90 percent of disease-causing genes.

A visualization of the data for cell populations in a sample, provided by DNA microscopy

Science

DNA microscopy offers a new way to image molecules

A completely new category of microscopy has been invented by researchers in the US. Dubbed DNA microscopy, the technique tags RNA molecules with a range of DNA "barcodes" which in turn flag the identity and location of the molecules, even when they're stacked on top of each other.

Newly discovered anti-CRISPR molecules can quickly inhibit the activity of the CRISPR-Cas9 gene editing process

Medical

Anti-CRISPR molecules discovered that can block the gene editing technology

New work from the Broad Institute and Brigham and Women's Hospital has presented a study that homes in on small molecules that may have the ability to safely block the CRISPR gene editing process.