In future, the Three Blind Mice might be able to avoid running into the farmer’s wife. In a study, scientists managed to restore vision in mice born with congenital blindness, using gene therapy to reprogram base retinal cells into functioning rod photoreceptors.
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"Giant” cancer cells contribute to many of the disease’s most dangerous abilities, but they remain relatively unstudied. Now, researchers from Brown University have investigated these troublemakers, revealing some physical characteristics that could eventually unlock new forms of treatment.
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Stanford scientists have shone the light on one kind of programmed cell death and watched on as the path of destruction was formed, with the speed on show offering vital clues as to the mechanics at play.
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A new study from researchers at the University of Exeter has shown how three specifically designed compounds can target the mitochondria in older human cells, effectively rejuvenating those cells and making them act young again to reverse key signs of aging.
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Current cancer treatments like chemotherapy and radiotherapy are designed to kill tumors, but they often take down healthy cells as well. An emerging technique could provide a more targeted approach, stopping tumerous cells from proliferating and effectively putting the cancer to sleep.
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We may be a step closer to new treatments for cystic fibrosis, as two research teams are now reporting the discovery of a new type of cell in the airways. These rare cells seem to be where most activity of a certain gene is located, mutations of which are known to cause cystic fibrosis.
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To improve our understanding and find new potential ways to treat Alzheimer's disease, researchers at Massachusetts General Hospital have produced one of the most detailed models of “Alzheimer’s-in-a-dish,” using cultures of human neural cells that display neuroinflammation.
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Scientists have created the most lifelike artificial embryos ever, guiding them through “the most important event in life” – a key development stage known as gastrulation. The researchers combined three types of mouse stem cells into an embryo that was just about ready to be implanted into a womb.
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Cancer cells have gone rogue and are dividing unchecked, and now Australian researchers have designed a new molecule that may put a stop to that. It targets a protein called PCNA, a donut-shaped structure that plays a key role in cell division, which could lead to a new class of cancer treatments.
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An emerging class of drugs called senolytics has been found to help restore the body to a more youthful state, and a new study has used a drug compound to extend the lifespan and improve the general health of older mice.
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