Chronic pain

People with fibromyalgia will soon have access to a new drug that treats the chronic pain condition's most elusive trigger: Poor sleep. Tonmya, a non-opioid under-the-tongue tablet, is the first FDA-approved drug for fibromyalgia in more than 15 years.

A subtle tweak in the way you walk – putting your toes in or out by a few degrees – could ease knee osteoarthritis pain and slow joint damage, according to new research that found personalized gait retraining can reduce strain on vulnerable cartilage.

Scientists have developed a non-opioid oral painkiller known as ADRIANA, the world's first α2B-adrenoceptor antagonist – which hasn't been targeted for analgesics before. It's provided powerful pain relief without sedation or risk of addiction.

Scientists have discovered a brain circuit that gives pain its emotional sting, explaining why some hurts linger as suffering. The breakthrough challenges our beliefs about how we process pain and may transform chronic pain treatments.

A current weight-loss and diabetes drug has become a surprise candidate for effective migraine treatment, with a new study showing that the GLP-1 receptor agonist provided significant relief to sufferers of these debilitating, severe headaches.

The simple act of walking every day can significantly reduce a person’s risk of developing chronic low back pain, according to a new study. But, its effectiveness depends on how long you walk for, and the speed at which you walk.

Diagnosing celiac disease often means exposure to the thing that makes you sick, which can be debilitating. It may soon be simpler and pain-free, with a first-of-a-kind test that can detect and gauge the severity of the disease in a test tube instead.

In the ongoing search to find an intervention that does away with opioids, a new game-based system has shown huge promise in tackling chronic neuropathic pain. Using a game and a headset, it "trains" patients to rewire brain signals to relieve pain.

A new study found that non-invasive in-ear electrical stimulation to the vagus nerve safely and effectively reduces osteoarthritis-related knee pain. It opens the door to innovative, quality-of-life-improving treatment.

A new experimental painkiller has shown promise in dulling or eliminating pain without the addictive qualities exhibited by today's most popular opioids. The drug also sidesteps common opioid side effects like constipation and sedation.

What if the key to reducing your chronic pain was not in tackling the symptoms, but in regulating your emotions? A study shows that retraining your brain to deescalate negative emotions could be an effective therapy for persistent pain.

A mainstay diabetes drug reduced pain and stiffness and improved function in overweight people with knee osteoarthritis, a new study has found. It may mean that, as a result, invasive knee replacement surgery can be delayed for as long as possible.