CRISPR

A new technique has been added to the CRISPR gene-editing toolbox. Known as PASTE, the system uses virus enzymes to “drag-and-drop” large sections of DNA into a genome, which could help treat a range of genetic diseases.

In a new study described as "seminal" and "pioneering", researchers in the US have successfully used CRISPR gene-editing technology to create personalized cancer-targeting immune cells, paving the way for future customized cancer treatments.

Scientists have demonstrated a new potential way to edit the genomes of bacteria in complex environments, by equipping viruses to hunt them down and insert the CRISPR gene-editing system.

Colossal has plans to resurrect the mammoth, and now it's revealed the second species on its de-extinction list – Australia’s lost thylacine. Partnering with a University of Melbourne lab, the project could revive the creature in about a decade.

Scientists have demonstrated an intriguing new variation on the CRISPR gene-editing system, which involves fixing a mutation on one chromosome by copying a healthy version from the other. “Nicking” the DNA also seemed to work better than cutting it.

As important as CRISPR-Cas9 gene-editing is, it has a relatively high error rate, which can introduce potentially harmful mutations. German researchers have now developed a more refined tool that reduces errors by nicking DNA instead of cutting it.

Incredible new data has revealed an experimental CRISPR gene editing therapy is both safe and effective up to three years after treatment. The results come from one of the longest running trials using CRISPR to treat a pair of rare blood diseases.

Researchers at the University of Maryland have developed a new gene-editing system they call CRISPR-Combo, which can edit multiple genes at once while also changing the expression of others in plants, to increase efficiency of genetic engineering.

Vitamin D deficiency is a growing health issue, but very few foods are rich in the nutrient. To help combat the problem, scientists have now used CRISPR gene editing to fortify tomatoes with vitamin D.

The biology behind social behavior may be more complex than we thought. Researchers have used CRISPR to block a certain neurochemical signaling pathway in hamsters, and found that the animals’ social behaviors changed in unexpected ways.

An intriguing new study has zeroed in on a brain region that is central to the development of both alcohol abuse and anxiety in adults, and demonstrated how gene editing could be used to wipe clean a person's predisposition to both disorders.

A single protein called Fel d 1 is responsible for the lion's share of human cat allergies, but a company called InBio says its initial research indicates a promising possibility that this protein can be eliminated safely using CRISPR gene editing.