DNA

Modified viruses have proven a handy way to get CRISPR/Cas9 gene editing materials into the nucleus of cells – but they're expensive, difficult to scale and potentially toxic. Now, researchers have found a non-viral approach that does the job better.

The first draft of a human “pangenome,” mapping out DNA variations in our genes, has been published. Building on the existing reference genome by adding 1,000 new gene mutations and 120 million base pairs, it's crucial for future genetic research.

Future data centers might switch to a storage medium that nature has been using for billions of years – DNA. In a major step towards making that a reality, scientists have created a new system of reading and organizing files using microcapsules.

Scientists have reconstructed the genomes of microbes from the Stone Age, and used them to produce new molecules. The complex puzzle was pieced together from DNA fragments of bacteria on the teeth of ancient humans and Neanderthals.

Scientists at UC San Diego have developed a way to potentially slow down the cellular aging process, using an oscillating genetic 'clock.' In tests, yeast cells were found to live significantly longer than those without.

A groundbreaking project has seen hundreds of scientists across the world uncover many mysteries of the evolution of mammals, work that may help us understand why humans are unique and what genetic changes may be key to some of our unique diseases.

Research which shows why DNA is repaired in certain cells but not in others could help ward off the ravages of aging, and diseases including cancer. It all hinges on a protein group called the DREAM complex.

Whole genomic mapping has offered scientists fresh insights into the behavior and development of Hodgkin lymphoma, and with new technology, the formerly expensive process could become fast, easy and accessible for understanding diseases.

If you want to know which animals are present in a given location, a good way of finding out is to look for their cast-off DNA. A new drone is designed to help scientists do so, by autonomously sticking itself to tree branches.

Researchers have resurrected ancient CRISPR proteins from millions and even billions of years ago. Not only can they still edit human cells, but they’re more versatile than modern versions, paving the way for new synthetic CRISPR gene-editing tools.

Researchers have developed a new open-source program that can convert drawings or digital models into nanoscale sculptures made of DNA. In tests, the system nailed rounded objects like vases and bowls.

Researchers in Japan have demonstrated a promising new cancer treatment. The team developed artificial DNA sequences shaped like hairpins that latch onto molecules overexpressed in cancer and trigger a strong immune response.