Fruit Flies

It's the size of a grain of sand, but the complex brain of this little insect has made history. The fruit fly's complete set of neurons and pathways has been captured in breathtaking detail, and is predicted to be a game changer across the science world.

Obesity is linked to several comorbidities, including musculoskeletal disorders. A recent study examined how time-restricted feeding in overweight fruit flies affected the factors underlying obesity’s effects on metabolism and muscle function.

Fruit flies differ from us in many ways, including the fact that they can't move their eyes relative to the rest of their head. That's not a problem, however, as new research shows that they move their retinas within their unmoving eyes instead.

Microgravity wreaks havoc on astronauts' biology, which is bad news for future space travel. A NASA experiment housing fruit flies on the International Space Station has now shown that artificial gravity can help reduce some of those health problems.

Researchers at Rice University have shown how they can hack the brains of fruit flies to make them remote controlled. The flies performed a specific action within a second of a command being sent to certain neurons in their brain.

Researchers at the University of Michigan have conducted studies in fruit flies and found that excess amounts of sugar can shut down crucial neural circuits linked to regulating satiety, possibly leading to overeating in humans.

The developing field of connectomics – the attempt to produce a neuron-and-synapse-level wiring diagram of the brain – has taken a major leap forward, as a Janelia team with the help of Google has released a full map of the hemibrain of a fruit fly.

Scientists have used the CRISPR gene-editing tool to give fruit flies a new evolutionary advantage – the ability to eat poison and store it in their bodies.

With Christmas just behind us and New Year’s around the corner, many are familiar with the effects of alcohol, but how it works in the brain is still shrouded in mystery. Now scientists at the Scripps Research Institute have discovered a new step in the intoxication process – by getting flies drunk.

A team has successfully developed a combination of herbal supplements and probiotics that can prolong the longevity of fruit flies by 60 percent. The technique is one of the first to successfully show a treatment that modulates the gut microbiome can result in potent lifespan-extending effects.

From the time we choose whether to hit the snooze button or get up, we make countless decisions every day, but just how the brain manages this mundane task is still shrouded in mystery. Now, researchers at Oxford University have observed in detail the mechanism that lets fruit flies make decisions.

Rather than focusing on a longer lifespan, it’s a better to improve our “healthspan,” the time we can enjoy good health. A new study from Brown University has linked the protein Sirt4 with an extended healthy lifespan in fruit flies, and the find may carry across to humans.