Genome

Researchers have resurrected woolly mammoth genes, from one of the last known mammoth populations, in the lab. These mammoths were believed to have suffered genetic defects, and in tests the team found that the genes did not function normally.

The Pan-Cancer Project is an international collaboration dedicated to analyzing thousands of whole cancer genomes. The results have been published, revealing new details about cancer’s causes, development, classification, diagnosis and treatment.

Scientists have extracted a complete human genome from a 5,700-year-old piece of "chewing gum." It was discovered that the chewer was an ancient female – now named Lola – with dark skin, blue eyes, and most likely a taste for duck and hazelnuts.

Researchers have managed to successfully edit the genes of lizards with CRISPR for the first time, turning them albino.

The human genome can tell us where we’ve come from, and it’s hiding more than a few surprises. Now researchers from the University of Adelaide have found evidence of two unknown, archaic human species in modern DNA.

Mitochondrial DNA in plants is so complex that scientists haven’t yet been able to edit the genes in there. Now a team of Japanese researchers has managed to do just that, which could help improve the genetic diversity of crops.

Humans are currently locked in an arms race against pathogenic bacteria – and we’re losing. Now scientists have identified the genes responsible for antibiotic resistance in a particularly dangerous superbug, and found a way to thwart them.

While exploring the “dark heart” of the human genome, geneticists have now found some of the most ancient pieces of DNA, inherited from Neanderthals and an as-yet-unknown human relative, which may be affecting our sense of smell to this day.

It’s no secret that tomatoes plucked from the supermarket aisles just aren’t that tasty. To find taste genes that could be spliced back into commercial crops, researchers have complied a pan-genome of all cultivated and related wild tomato species, uncovering almost 5,000 previously-unknown genes.

NASA has conducted a comprehensive study comparing the genes and biology of identical twins Scott and Mark Kelly, after Scott spent almost a year in space while Mark stayed on Earth as a control. And now the results of that study have finally been released.

CRISPR-Cas9 acts like a pair of molecular scissors and enables precise cut-and-paste DNA edits. But now, researchers have developed a new genetic tool that, they say, acts more like a motorized DNA “shredder.”

Scientists have created the first fully computer-generated genome of a living organism. Named Caulobacter ethensis-2.0, it was built by simplifying the natural code of Caulobacter crescentus. The team says this is a huge step towards creating completely synthetic life and medicinal DNA molecules.