Gladstone Institutes

Researchers have studied a protein linked with Alzheimer's, and found just how it damages the brain and how that can be reversed

Scientists neutralize and reverse a key genetic risk factor for Alzheimer's

One of the clearest Alzheimer's risk factors is the gene apoE4. New research has peered closer at the protein encoded by this gene and uncovered how it affects the brain, how it increases the risks of Alzheimer’s and most importantly, how the damage can be reversed.

The study found that amyloid-beta plaques in the brain reduce levels on the protein BRCA1 (red) in neurons (blue)

Alzheimer's & Dementia

Scientists identify protein central to cognitive decline associated with Alzheimer's disease

Researchers have studied the protein BRCA1, using a combination of tests on laboratory mice and human brain tissue to determine that the protein is central to learning and retaining memories. It's study is important in understanding the cognitive decline associated with Alzheimer's.

Diabetes

Producing insulin-secreting pancreas cells from skin cells gives hope to diabetics

Scientists at Gladstone Institutes in San Francisco have provided hope for a more permanent treatment for diabetes by developing a technique to reprogram skin cells into insulin-producing beta cells.