Heart attack

Atherosclerosis is a disease where fatty plaques build up in the arteries, increasing risk of heart attack or stroke. But now, researchers at Oxford have found a protein that could be targeted in new prevention drugs for these deadly buildups.

Atherosclerotic plaque-deposits on the inner walls of arteries are a frequent cause of heart attacks and strokes. A newly-developed nanoparticle could help minimize those deposits, as it prompts the body's own cells to "eat" them.

Even if one survives a heart attack, the formation of thick scar tissue can increase the chance of heart failure. Now researchers have found a way to improve the quality of scar tissue in animal models, resulting in improved heart function.

​Considering how important an organ it is, it’s a shame that the heart is so bad at repairing itself. Stem cells are an emerging solution, and now researchers at the Universities of Cambridge and Washington have combined heart muscle cells and supportive cells to help mend broken hearts.

Cardiovascular diseases are the number one killer in the world – and we might have a two million year old ancestor to blame. A team pinpointed a single gene that ancient ancestors lost, which appears to have predisposed us as a species towards higher rates of atherosclerosis than other apes.

The heart is notoriously fragile, having quite a lot of difficulty in repairing itself after sustaining damage. But now, researchers from the University of Calgary have found a previously unidentified cell population in the fluid that surrounds the heart, which seems to help heal injuries.

After a heart attack this vital organ remains damaged, which can eventually lead to heart failure and death. Now, researchers have managed to use placental stem cells to regenerate heart cells in mice, which could lead to groundbreaking new treatments for heart attack victims.

The main risk factors for heart disease are lifestyle choices like a bad diet, smoking, lack of exercise – and poor sleep. That last point has gone relatively unstudied, but new research out of Harvard has found the chemical chain reaction that links disrupted sleep and cardiovascular disease.

Whether or not cardiac stem cells exist has been up for debate, but now European scientists claim to have created a cell-by-cell map of a mouse heart before and after a heart attack – and found no evidence of stem cells at all.

​After a heart attack, the heart's damaged muscle tissue is replaced by non-beating scar tissue. Unfortunately, this leaves the muscle permanently weakened. There could be new hope, however, as scientists have taken strides toward understanding how a fish is able to heal its own heart.

A newly developed smartphone app has shown promise for determining if a person is suffering from a serious heart attack. A study into the app's accuracy revealed it was almost as effective as a traditional electrocardiogram (ECG)​ at identifying a serious form of heart attack.

​When a clot blocks a blood vessel in the heart, a heart attack is the unfortunate result. Frequently, surgery is required in order to remove that clot. Thanks to an experimental new drug-delivery system, however, that approach may become increasingly unnecessary.