Insulin

New research from Tufts University may make it a little easier to manage diabetes. In mouse tests, the team implanted beta cells that produce more insulin on demand, when they’re activated by blue light.

A team at MIT has developed a new capsule that would survive a trip through the stomach and deliver its drug payload to the lining of the small intestine via microneedles.

New research demonstrates how a high-fat diet can disrupt levels of an intestinal immune cell known to help regulate microbial populations in the gut. The study shows how low-levels of this molecule result in increased growth of harmful gut bacteria, leading to inflammation and insulin resistance.

What if you could stay healthier without changing your diet? In mouse tests researchers have now found a way to alter the fat metabolism in the liver, reducing the chances of diabetes without changing a high-fat diet.

Medical scientists have made a promising breakthrough in diabetes research, describing a novel technology that converts stem cells into insulin-secreting beta cells by harnessing an often overlooked step in their maturation.

Plenty of work has gone into developing an insulin pill as an alternative to injections, but that comes with its own challenges. Now, an MIT team has created a new design for a capsule that houses a microneedle made of insulin, which injects the hormone through the stomach lining.

A possible diabetes cure could be found by replenishing a patient’s own supply of beta cells, which naturally produce insulin. Researchers at Washington University in St. Louis are a step closer to that kind of treatment, after tweaking the recipe for turning stem cells into beta cells.

A new study led by Stanford scientists forewarns of massive gaps in access to the life-saving hormone insulin as the diabetes epidemic continues to worsen. So much so, that half of those who need it simply might not be able to get it.​

Researchers have discovered a new way to reduce the risk of diabetes – sugar. Trehalose is a natural sugar that has now been found to deprive the liver of glucose and activate a gene that improves insulin sensitivity and triggers the burning of more fat.

New research by a team of Australian scientists has unexpectedly revealed a novel anti-obesity drug. Initially working to create a drug that prevents insulin resistance the researchers discovered in early animal tests that it instead prevented the animals from depositing and storing fat.

For a long time, insulin injections have simply been a fact of life for people – including babies – suffering from neonatal diabetes. But a new 10-year study has now shown tablets to be just as effective, with recipients hailing the new approach as a "miracle treatment."

Orally administered insulin, a game-changing treatment, is one step closer to reality with a final Phase 2b human clinical trial underway to prove the drug's efficacy before it reaches the final stages of trials and registrations that could bring it to market within a few short years.