Lung cancer

A Phase 2 clinical trial of immunotherapy drug tarlatamab, produced promising results in patients with small cell lung cancer, a particularly aggressive form of cancer, for whom previous treatments haven't worked.

That a new cancer trial is about to start in the US is positive but not out of the ordinary, right? Except it is. This trial will be one of the first undertaken in a real-world clinical setting and represents a new model for future clinical trials.

Scientists have long known that the engine room of cells, the mitochondria, play an essential role in the growth of cancer. Now, they have the clearest picture yet of just how the energy organelles form complex structures within lung cancer tumors.

Extraordinary research has presented a new hypothesis as to how cancer develops, inspired by a forgotten study from 75 years ago. The research showed how pre-existing mutations in healthy tissue can be prompted into tumorous proliferation by air pollution.

Small cell lung cancer (SCLC) is one of the deadliest forms of the disease, but now scientists may have a promising new avenue for treatment. By combining a new drug with an outdated one, the team found that they could halt growth of tumors in mice.

A first-of-its-kind study has investigated the link between certain cancers and people living in close proximity to wildfires. The findings revealed higher rates of brain tumors and lung cancer in populations living within 50 km (31 miles) of a wildfire.

A thin new robot developed at the University of Leeds designed to diagnose and treat cancer takes the shape of a tentacle, which can be magnetically guided into the depths of the lungs to inspect suspicious lesions or deliver drugs.

A new study is showing a novel blood test can detect the presence of lung cancer with over 90 percent accuracy. The test uses artificial intelligence to identify abnormal patterns in fragments of cancer DNA circulating in a patient’s bloodstream.

Difficult to detect and with a low survival rate, pancreatic cancer is one of the most insidious forms of the disease. But now, researchers have identified an existing drug that could fight pancreatic cancer by targeting a key gene mutation.

Cancer spreads easily, and a common location for secondary tumors to appear is the lungs. Now, scientists at Harvard’s Wyss Institute have developed a way to treat metastatic tumors in the lungs, by attaching immune-baiting drugs to red blood cells.

Urine tests that pick up biomarkers of cancer are one way scientists hope to diagnose the disease early, and MIT researchers have demonstrated a particularly promising example that could give efforts to diagnose early-stage lung cancer a huge boost.

Australian researchers have affirmed an unusual, almost paradoxical, observation that cancer patients with high body mass index tend to display greater survival rates than patients with average healthy weights.