Osteoarthritis

Treatments for osteoarthritis-related knee pain range from medication all the way up to knee joint replacement. The recently trialled Misha Knee System is intended to help fill the gap between those extremes, by acting as an implanted shock absorber.

When it comes to the different ways of exercising the human body, walking is about as accessible as they come, and new research suggests it could be a powerful way to tackle osteoarthritis in the knees.

Scientists have developed an injectable gel that can prevent a form of injury-triggered osteoarthritis taking hold, by allowing for sustained delivery of drugs in the damaged joints to keep inflammation at bay.

Researchers have identified a signaling pathway involved with osteoarthritis pain. A study in mice found that normal limb use returned after this pathway was blocked, which could lead to new pain treatments for patients with osteoarthritis.

By stimulating cells to reproduce, electricity has already been shown to help heal soft tissue injuries. Now, an electricity-producing implantable material likewise appears to boost the regrowth of cartilage in compromised joints.

Ice in and of itself isn't slippery – it becomes slippery when friction causes a thin layer of liquid water to form on top of it. Scientists have now applied that same principle to an injectable medication that could be used to treat osteoarthritis.

A new, dissolving, textile-based stem cell implant has reduced pain and restored hip joint function to dogs with moderate osteoarthritis, in what researchers say could be a first step toward less invasive joint resurfacing in dogs as well as humans.

Scientists have demonstrated how engineered nasal tissue can not only act as structural reinforcement for troublesome joints, but also how its unique properties can counter inflammation in severe osteoarthritis.

Scientists in China have just demonstrated how a newly developed "cryogel" can be used to bolster stem cell therapy to tackle osteoarthritis, demonstrating its effectiveness by reversing the condition in mice.

Researchers at Pennsylvania State University studying an approved anti-depressant drug have found it can interfere in the chain of events leading to osteoarthritis, halting its progress and even promoting the regeneration of cartilage.

Although anti-inflammatory drugs can be used to tackle conditions like osteoarthritis, there are downsides to our current methods of delivery. New research at the Washington University School of Medicine in St. Louis could address these shortcomings.

A compelling new study, led by scientists from Washington University School of Medicine in St. Louis, has found a novel gene therapy can prevent obesity and build muscle without the need for additional exercise, in mice being fed a high-fat diet.