Scripps Research Institute

Researchers have developed an antibody that targets the opioid fentanyl and its derivatives, reversing overdose better than currently available treatments. The novel therapy could be a more effective way of treating life-threatening opioid overdoses.

In addition to causing health problems, injury and death, excessive use of alcohol harms individuals, families, and society. A new study found that an anti-inflammatory medication used to treat psoriasis might effectively combat problem drinking.

Immune suppression can help relieve symptoms of autoimmune diseases, but it can cause complications. A new nanoparticle therapy selectively targets problematic immune cells, and was able to significantly delay and even prevent arthritis in mice.

Our deepening understanding of the different types of fat continues to present new ways to potentially manipulate metabolic processes for better health outcomes, and new research on an existing asthma drug has opened up a promising new pathway.

An incredible new study has discovered a novel communication pathway between fat cells and the brain. The findings reveal that the brain can directly send messages to fat tissue and influence metabolic processes.

Exactly how non-living molecules sparked life is one of the most puzzling mysteries of science. Scientists have now discovered chemical reactions that can produce the building blocks of life out of materials common in early Earth's primordial soup.

Scientists at Scripps Research investigating the cellular basis for itching have made an important discovery around the role of a certain protein, and one that could lead to new treatments of chronic conditions like eczema.

Scientists at Scripps Research have pinpointed a brain protein they suggest plays an important role in the anxiety experienced during alcohol withdrawal, and could be targeted for future treatments to prevent relapse.

A new smartphone app called MyGeneRank has been developed by scientists at the Scripps Research Institute. The app calculates a person’s genetic risk for coronary artery disease and directs those found to be at high risk to appropriate medical advice.

Scientists at the Scripps Research Institute have demonstrated how a natural signaling pathway can be temporarily activated to improve metabolic health in obese mice, blocking the deleterious effects of a high-fat diet.

A new study has expanded our knowledge of the relationship between brain cholesterol and Alzheimers, by observing how one influences the other in live mice and demonstrating how the process could be manipulated to slow the disease.

An Antarctic lake holding twice the volume of water as San Diego Bay in California has vanished after 600 to 750 million cubic meters of water drained through the ice and into the ocean during the 2019 Antarctic winter.