Tumor

Preliminary results from an ongoing Phase 1/2 human trial indicate a new drug dubbed OMO-103 can safely and effectively inhibit the function of a gene known to drive the growth of many common forms of cancer.

Scientists at the University of California San Francisco have found a way to fight one of the most common cancer-causing mutations. The new drug puts up an “eat me” marker that can help the immune system or other drugs find and kill the cancer.

Earlier this year, scientists demonstrated "drug factory" beads that could be implanted alongside ovarian and colorectal tumors in mice to destroy them in less than a week. A new study focusing on another cancer type has now produced similar results.

Researchers have created a new mRNA vaccine for cancer that’s designed to carry its cargo to the lymph nodes rather than the liver. Tests in mice showed significant inhibition of the tumors, with complete remission in a decent percentage of cases.

Scientists in Spain have uncovered a mechanism behind why some cancer patients don’t respond well to treatments – and more importantly, found a “weak spot” that could be targeted by existing drugs.

A research team working to better understand the movements of cancerous cells has made an important breakthrough, describing a "sweet spot" where these cells like to congregate, which could reveal new ways to stop them in their tracks.

Researchers have found that adding a booster protein can significantly improve the outcome of cancer immunotherapy. Tests in mice showed the protein produced 10,000 times more cancer-targeting immune cells, with all mice surviving the experiment.

A new study has demonstrated how nanoparticles can be used as a type of mechanical drug inside cells to impair function and cause their demise, which could be used to target cancer while leaving healthy cells unharmed.

Scientists exploring the potential of spider silk in next-generation cancer therapies have found yet another use for the natural material, using it to stabilize and enhance a cancer-killing protein known as the "guardian of the genome."

Modifications to an existing drug promise to avoid toxic side effects brought on when treating a common and deadly form of cancer, with the scientists hailing the breakthrough as a potential "home run" for next-generation treatments.

Researchers at the Tokyo University of Science have demonstrated a low-cost and highly promising form of nanoparticle technology, using corn and water as a starting point for a novel "bionanoparticle" that suppresses tumor growth in mice.

Heightened tissue growth can result when cells come under tension, and a new study on cancer cells has pinpointed the biological mechanism that drives this process, which the authors believe can be targeted to prevent tumor development.