University of California San Francisco

People suffering from major depressive disorder (MDD) are also more likely to have higher body temperatures, finds the largest study of its kind – and surprisingly, one suggested treatment is to heat the body up even more, with saunas and hot yoga.

A genetic mutation that triggers a 'molecular domino effect' causing hearing loss mirrors the same kind of noise- and age-related damage. Inhibiting a single molecular response has the potential to protect all ears from a common form of hearing loss.

New research has found that elevation of a biomarker predicts the worsening of multiple sclerosis disability up to two years before it occurs, providing a timeframe in which interventions can be implemented to prevent or slow worsening disability.

A new study has found direct evidence that an over-the-counter antihistamine can repair the protective nerve sheath that’s damaged in people with multiple sclerosis, opening the door to a potential new treatment for the debilitating disease.

Researchers have created a synthetic “cellular glue” that bonds cells together to different degrees. The technique could speed up wound healing, even in tissues that don’t heal well naturally, and eventually allow scientists to build better organs.

New data suggests long-term use of non-steroidal anti-inflammatory drugs, such as naproxen or ibuprofen, can be associated with hastened progression of osteoarthritis symptoms. The researchers are cautious to stress the link is still observational.

Senescent cells are blamed for many effects of aging and as such, they’re targeted by a range of anti-aging therapies. But we might not want to wipe them all out, as a new study suggests that some senescent cells play positive roles in healing.

Scientists at the University of California San Francisco have found a way to fight one of the most common cancer-causing mutations. The new drug puts up an “eat me” marker that can help the immune system or other drugs find and kill the cancer.

Modifications to an existing drug promise to avoid toxic side effects brought on when treating a common and deadly form of cancer, with the scientists hailing the breakthrough as a potential "home run" for next-generation treatments.

A new molecule may help reduce side effects in a drug that could treat alcohol use disorder. Essentially, the molecule disarms the drug in most of the body, but can’t cross the blood-brain barrier, letting the drug get to work in the brain only.

Scientists studying the mechanisms behind cellular stress and its effects on aging have found success in reversing cognitive decline in mice using an experimental drug, which bodes well for further study of aging and its effects in human subjects.

A growing body of study is beginning to suggest severe apathy in older adults is an early sign of dementia. New research is now presenting one of the first longitudinal studies to show apathy could be an early symptom of cognitive decline.