University of Oxford

Scientists investigating new treatments for hand osteoarthritis have made promising new inroads through research on a drug originally developed for acne and psoriasis, with work now underway to ascertain its potential as a new clinical therapy.

Two new studies offer some of the strongest evidence to date for a relationship between depression and gut bacteria. The studies do not claim causality but do suggest a strong correlation that could inform novel diagnostic biomarkers for depression.

A case study has tracked, for the first time, the movement of antibiotic-resistant bacteria from a patient's gut microbiome to their lungs. The research presents the first direct evidence of this transmission pathway taking place in hospital patients.

A study has shed light on the mystery of how high blood glucose leads to type 2 diabetes. The discovery reveals glucose metabolites can damage insulin-producing pancreatic beta cells, and disrupting this process could offer a way to treat the disease.

New analysis of a volcanic eruption off the coast of Tonga earlier this year has revealed the true extent of the massive explosion, and established its plume as the highest on record and the first recorded entering the mesosphere.

Compelling new research has homed in on a genetic variant that seems to play a significant role in how well people generate an immune response to COVID-19 vaccines and their chances of experiencing a breakthrough infection in the year after vaccination.

University of Oxford physicists have linked two atomic clocks through quantum entanglement for the first time. The feat can help make these clocks so precise that they begin to approach the fundamental limit of precision set by quantum mechanics.

A meta-analysis encompassing more than 150,000 participants has concluded muscle pain or weakness is not a common side effect from statin drug therapy and should not influence whether a person ceases the treatment.

New research has offered the most comprehensive look at the long-term neurological effects of COVID-19 to date, tracking more than one million people and finding increased rates of dementia can be detected up to 24 months after the acute disease.

A new single-shot rabies vaccine is showing promising results following a Phase 1 human clinical trial. Further clinical trials are now underway in the hopes the vaccine could help cut down the thousands of deaths every year from this viral disease.

A comprehensive new Oxford study has added to the growing body of research highlighting the health effects of alcohol. The large-scale genetic analysis suggests that alcohol consumption directly accelerates aging, by shortening telomeres.

A study has reviewed more than 150 clinical trials to present a comparative analysis of 30 drug treatments for insomnia. The findings indicate many lack long-term safety data and treatments such as melatonin have little evidence of effectiveness.