Virus

A clinical trial taking place in the Democratic Republic of the Congo has been terminated early due to the success of two drugs being investigated to treat the Ebola virus. The two drugs have displayed incredible survival rates, especially if given at the earliest stages of infection.

A compelling new study has described a novel association between viral infections, neurodegenerative disease, the gut microbiome, and our immune system. The research suggests gut bacteria disruptions can allow harmful viruses to trigger neurological diseases such as multiple sclerosis.

There exists a group of HIV-positive people who have a rare ability to naturally control the HIV infection. Now, after years of research, a team of scientists from the Institut Pasteur in Paris, has successfully reprogrammed cells that lack this ability, giving them the same, antiviral potency.

By guiding evolution, scientists have managed to manipulate micro-organisms into producing useful new drugs and materials, but it’s a time-consuming process. Now, UNC researchers have developed a new tool that speeds up the process in mammalian cells, creating new therapeutics in a matter of days.

An early-stage study has found a strain of the common cold virus can effectively target and destroy bladder cancer cells. This phase 1 human trial suggests the virus directly induces tumor cell death, and if verified by larger trials could be used in conjunction with other immunotherapy treatments.

The over-prescription of antibiotics is a major problem in the world today, leading to the dramatic rise of antibiotic-resistant bacteria. New research is suggesting not only are antibiotics ineffective for individuals suffering from influenza, but they can worsen the initial viral infection.

Researchers have uncovered a new weakness that could be exploited to produce new antiviral drugs. The team discovered a compound that can prevent certain classes of viruses from infecting cells, paving the way for new treatments against diseases like the common cold, meningitis or polio.

An intriguing new study has described a mechanism by which virus particles can interact with proteins in biological fluids and become more infectious, while also accelerating the formation of plaques often associated with neurodegenerative diseases such as Alzheimer’s.

What happens when the vastly different worlds of modern art and computer malware collide? The answer is an installation called The Persistence of Chaos, and it just sold at auction for US$1.345 million.

Unfortunately stem cells lack some of the self-defense mechanisms that other cells have, leaving them open to attack from viruses and other threats. Now, researchers from the University of Edinburgh may have found a way to switch this mechanism back on, making stem cell treatments more effective.

​If the mosquitos in a given area are carrying a potentially lethal virus, then the sooner that local health authorities know about it, the better. According to new research, traps that collect the insects' liquid waste may allow that to happen – and cheaply, too.

Bacteria can share genes with each other to quickly develop resistance to antibiotics. A new genetic study of bacteria from around the world has found that isolated populations share incredibly similar “molecular memories,” suggesting they’re basically flying around the world to spread their genes.