Weight Loss

Scientists have drawn up an alternative approach to tackle obesity that retrains the minds of people highly responsive to food cues to resist cravings, and demonstrated that it may outperform current go-to strategies for long-term weight loss.

A team at Australia's Edith Cowan University have shown that when combined with the right diet, resistance training such as body-weight exercises or lifting dumbbells, can have similar effects to aerobic exercise when it comes to burning fat.

Preliminary data from a large Phase 3 clinical trial is offering promising signs for a new anti-obesity drug. Called tirzepatide, the drug helped overweight and obese participants lose up to 22.5 percent of their total body weight over 72 weeks.

In one of the longest trials of its type ever conducted researchers have found limiting food intake to a short period of time every day, known as time-restricted feeding, is no more effective a weight loss strategy than simple calorie counting.

By studying the behavior of a protein tightly linked with a wide range of cancers, scientists have uncovered the role it plays in regulating body weight, deepening our understanding of the way our bodies respond to food.

While some folks might say that obese people should just exercise more and eat less, things aren't always quite that simple. A new implant is thus being designed to help boost the weight-loss process, by killing hunger-inducing cells in the stomach.

Preliminary research results have offered some compelling new answers around how exercise can affect sleep, demonstrating how favoring resistance-style workouts like weightlifting can bring about the most significant improvements.

Through experiments involving a drug originally developed to suppress the growth of tumors, scientists have happened upon a potential new anti-obesity treatment, which they've demonstrated can trigger weight loss in mice.

Scientists have found that extending the nightly sleep duration of overweight subjects can lead to a significant reduction in daily calorie intake, so much so it could drive significant weight loss if the pattern was sustained over the long term.

A new study has shown how targeting an enzyme within fat cells can alter sensitivity to leptin – a hormone that plays a key role in appetite regulation – and in turn drive rapid weight loss in obese mice, while also improving overall metabolic health.

Weight gain following quitting smoking is such a common phenomenon it is often cited as one of the main reasons people are hesitant to quit. A study has now discovered how the microbiome may influence weight gain associated with the cessation of smoking.

Recent studies have shown how the compound celastrol can tackle obesity in mice, but with harmful side effects. A new understanding of how the compound works on a cellular level could allow these effects to be avoided.