Weight Loss

Researchers have added another discovery to the long list of adverse effects from high fat intake: a disruption in brain cells that regulate how rat stomachs fill and empty. The finding could have implications in the battle against obesity.

A study following the eating habits of 500 people found weight change is most affected by the size and frequency of meals rather than the interval from first to last meal. The study challenges the belief intermittent fasting is a useful weight loss tool.

Following successful trials in adults and subsequent FDA approval last year, an emerging obesity drug has now shown promise in overweight adolescents, inducing similar weight loss effects in this younger cohort.

A study has examined the effects of “front-loaded” diets that hinge on a heavy breakfast, finding that while they offer no real weight-loss potential, they may suppress our appetite throughout the day.

A study testing time-restricted eating has delivered positive results, indicating greater weight loss compared to calorie counting but researchers are still unsure whether the benefits are due to anything more than participants simply eating less.

By taking a proven migraine drug and experimenting on its potential to temper food intake, scientists have demonstrated how it can be used to regulate appetite and drive down body weight in obese mice.

An international team of researchers experimenting with the function of the endocannabinoid system have shown how it can be manipulated to combat obesity with the help of a synthetic peptide.

In the quest to tackle obesity, a new study has brought a new molecule into the mix. The authors were able to demonstrate how the molecule can be targeted with treatments to prevent weight gain in mice on high-fat diets.

Scientists probing the functions of neurons known to play a central role in hunger sensation have discovered a novel signaling pathway by which they influence tendencies to binge eat, raising the prospect of using drugs to temper food cravings.

Researchers continue to unravel the complex role inflammation plays in obesity, now demonstrating how cold temperatures can stimulate the release of a molecule that reverses this type of inflammation and reduces body weight in mice.

Scientists digging into the molecular details of the relationship between exercise and weight loss have made a significant discovery, pinpointing a modified amino acid that spikes in the blood following intense workouts and suppresses appetite.

Scientists at Hong Kong Baptist University have identified an enzyme that is a key regulator of satiety and appetite, and shown how inhibiting its activity can protect against weight-gain in mouse models of obesity.