Weight Loss

A study has examined the effects of “front-loaded” diets that hinge on a heavy breakfast, finding that while they offer no real weight-loss potential, they may suppress our appetite throughout the day.

A study testing time-restricted eating has delivered positive results, indicating greater weight loss compared to calorie counting but researchers are still unsure whether the benefits are due to anything more than participants simply eating less.

By taking a proven migraine drug and experimenting on its potential to temper food intake, scientists have demonstrated how it can be used to regulate appetite and drive down body weight in obese mice.

An international team of researchers experimenting with the function of the endocannabinoid system have shown how it can be manipulated to combat obesity with the help of a synthetic peptide.

In the quest to tackle obesity, a new study has brought a new molecule into the mix. The authors were able to demonstrate how the molecule can be targeted with treatments to prevent weight gain in mice on high-fat diets.

Scientists probing the functions of neurons known to play a central role in hunger sensation have discovered a novel signaling pathway by which they influence tendencies to binge eat, raising the prospect of using drugs to temper food cravings.

Researchers continue to unravel the complex role inflammation plays in obesity, now demonstrating how cold temperatures can stimulate the release of a molecule that reverses this type of inflammation and reduces body weight in mice.

Scientists digging into the molecular details of the relationship between exercise and weight loss have made a significant discovery, pinpointing a modified amino acid that spikes in the blood following intense workouts and suppresses appetite.

Scientists at Hong Kong Baptist University have identified an enzyme that is a key regulator of satiety and appetite, and shown how inhibiting its activity can protect against weight-gain in mouse models of obesity.

Scientists have drawn up an alternative approach to tackle obesity that retrains the minds of people highly responsive to food cues to resist cravings, and demonstrated that it may outperform current go-to strategies for long-term weight loss.

A team at Australia's Edith Cowan University have shown that when combined with the right diet, resistance training such as body-weight exercises or lifting dumbbells, can have similar effects to aerobic exercise when it comes to burning fat.

Preliminary data from a large Phase 3 clinical trial is offering promising signs for a new anti-obesity drug. Called tirzepatide, the drug helped overweight and obese participants lose up to 22.5 percent of their total body weight over 72 weeks.