Alzheimer's & Dementia

Nanotech said to boost the bioavailabilty of curcumin

Nanotech said to boost the bioavailabilty of curcumin
Curcumin is obtained from turmeric, pictured here
Curcumin is obtained from turmeric, pictured here
View 1 Image
Curcumin is obtained from turmeric, pictured here
1/1
Curcumin is obtained from turmeric, pictured here

If you like spicy foods, then you're probably aware of the claimed anti-inflammatory qualities of turmeric. Scientists have now developed what they say is a more effective way of biologically delivering turmeric's active compound, curcumin.

Among other things, curcumin is said to help in the treatment of chronic health problems such as heart disease, cancer and Alzheimer's.

However, when turmeric is ingested in its regular powdered form, only a limited amount of the curcumin in it gets absorbed by the body. Working with colleagues from Texas A&M University and Canada's McMaster University, researchers at the University of South Australia therefore set out to create an alternative.

The team ultimately developed a new process for producing minuscule curcumin-loaded nanoparticles. In lab tests, these were reportedly found to increase the oral bioavailability of curcumin by 117 percent, delivering the compound directly into human cells.

Subsequent animal trials suggested that ingestion of the nanoparticles was effective at preventing and even reversing cognitive deterioration. The curcumin is claimed to do so by suppressing oxidative stress and inflammation, and by helping to remove Alzheimer's-associated amyloid plaques in the brain.

Now, in the latest phase of the study, the curcumin nanoparticles are additionally being tested as a means of preventing the spread of genital herpes.

The research is described in a paper that was recently published in the International Journal of Molecular Sciences.

Source: University of South Australia via EurekAlert

9 comments
9 comments
nick101
Great! So, um, are we waiting months, years, decades, for this?
Baba Jaiy
Why is the article started with the question if does one like spicy foods? Turmeric is not spicey. It is primarily astringent and in the typical powdered form is rather bland.
James
In the UK I buy so called "bio-fermented" turmeric.

The theory is that it is broken down more than the turmeric powder and absorbs much easier.
They advise that it is best taken on an empty stomach, whereas the powder needs to be taken with a meal that contains fat (as the powder absorbs into the fat and then the fat is what the gut absorbs).

Both forms help a family member's Crohn's disease, and I believe the fermented form is more effective but that may be because it's taken more often/more regularly.
RobertElliot
That sounds great & with the flavour aspect as well I will be in the market for it,
Dee Simpson
Black pepper added to it strangely enough increases bioavailability much more than 117%. No need for prescription nano-particles.
Theodore41
@Dale Simpson.
Could you please write more about it?
IvanWashington
what if this new form is still augmented further with piperine?
Martin Hone
This story a bit light on information. Anyway, I take a teaspoon of turmeric powder everyday with a spoon of coconut oil and a sprinkle of ground black pepper in a large glass of warm water with a dash of apple cider vinegar. The oil and black pepper supposedly combine with the turmeric to aid absorption.
dcris
A pinch of black pepper makes it bio available. Or actually cooking with it...heat apparently is the trick too. I just mixed up a batch and add a guess of a pinch of pepper so it's always good to go. Simple, no Nano required.