Cancer

A new meta-analysis has found a positive correlation between higher levels of coffee consumption and lower risk of prostate cancer. The research hopes to help bring clarity to an area of study with deeply inconsistent results.

A compelling study is suggesting all cancer cells may have the capacity to enter states of dormancy as a survival mechanism to avoid destruction from chemotherapy. And the mechanism these cells deploy notably resembles one used by hibernating animals.

CAR T cell immunotherapy is a promising cancer treatment that supercharges natural tumor-hunting cells, but it can backfire with potentially deadly results. Now, scientists have engineered off switches for these immune cells.

A new study led by researchers from University College London suggests that combining traditional chemotherapy with an experimental therapy that uses magnetic nanoparticles to heat tumor cells could significantly enhance the efficacy of both treatments.

Killing cancer cells isn’t too hard – the tricky part is doing so without harming healthy cells. Now researchers have developed nanoparticles that selectively release drugs inside tumors, while keeping them safely locked away when in healthy cells.

Cancer cells are very energy-hungry, which could be a potential weakness. Now, researchers have developed an experimental drug that blocks mitochondrial metabolism, starving cancer cells of energy while leaving healthy cells relatively unscathed.

A new Harvard study highlights missing pieces of the puzzle in the relationship between cancer and obesity. The team finds that cancer cells can use the higher fat availability to starve immune cells of fuel and prevent them from targeting tumors.

It’s long been thought that our cells stop dividing as we age as a natural preventative measure against cancer. Now a new study has found intriguing evidence supporting this hypothesis in genomes from several particularly cancer-prone families.

Dormant tumor cells can sit quietly for years but exactly what reactivates these sleeping cancer cells is unknown. A new study is offering a novel hypothesis, suggesting stress hormones can trigger a chain of events that reawaken these dormant cells.

EPFL scientists have demonstrated a new method to make immunotherapy more effective and directed against cancer. The team designed microparticles containing drugs that are only released when T cells physically squeeze them, on contact with cancer.

Oncolytic viruses selectively kill cancer cells, but this can be ineffective if it alerts the immune system. Now scientists have tweaked these viruses to avoid detection by the immune system, allowing them to track down cancer even after it’s spread.

A novel cancer vaccine is moving to Phase 1 human trials in the US after results from animal studies showed encouraging efficacy and a robust safety profile. A new study describes the vaccine as producing complete responses in 90 percent of animals.