Cancer

One of cancer’s crafty tricks involves manipulating the host’s immune cells to protect tumors instead of fighting them. Now researchers at Massachusetts General Hospital have turned the tables again, transforming these cells back into cancer killers.

Researchers in Canada have made a significant discovery relating to pancreatic cancer, pinpointing a protein that the cancer cells rely on for growth, and demonstrating how targeting them can inhibit tumor growth in the lab.

Researchers at Indiana University have linked a protein secreted by the stomach to obesity. In tests in mice, the team switched off the protein and found that it reduced the animals’ body fat levels, even when fed a high-fat diet.

Scientists have developed a tiny first-of-its-kind imaging sensor designed to build detailed 3D maps of cellular structures inside the body, potentially revealing stiffness and abnormalities that may be indicative of cancer.

Scientists at Cambridge have demonstrated a new method to fight leukemia, by targeting overactive enzymes that can lead to the disease. If the results of mice tests carry across to humans, it could be the first of a new class of cancer drugs.

We all know exercise is good for us, but recently, scientific studies have started to shine a light on how regular physical activity can benefit human health in ways you might not expect. Let's take a look at some interesting examples.

Several hundred million people around the world have safely received a wildly effective COVID-19 vaccine based on mRNA technology. So what exactly is an mRNA vaccine, where did the technology come from, and what other diseases could it be useful for?

Lockdowns, lab closures, funding cuts, and delays to ongoing clinical trials have all contributed to cancer research disruptions that may set the field back two years, according to new estimates made by the Institute of Cancer Research in London.

Scientists at Purdue University and Scripps have identified a natural compound from a common shrub that could help fight cancer. The compound is the first found to inhibit a cancer protein that was previously considered “undruggable.”

Scientists at Sweden's Linköping University have developed a new tool to tackle risky remnants of malignant brain tumors, demonstrating how an ion pump can take highly effective chemotherapy drugs directly to the source of the problem.

A new review article is presenting a promising case for phenformin, an old diabetes drug related to metformin, being repurposed as an adjunct to new immunotherapy cancer treatments. A phase 1 clinical trial is underway to test the novel combination.

Scientists in Japan have developed a versatile new hydrogel that can be packed with cancer-fighting drugs and triggered to release their payload in response to temperature and pH changes in the tumor microenvironment.