Cholesterol

Medical

Positive human trial results for promising new cholesterol-lowering drug

An entirely new cholesterol-lowering drug is on track for broad clinical approval after the latest trial results to be published reveal it is both safe and effective when administered in conjunction with commonly prescribed statins.

Researchers from the University of Pennsylvania have lowered the blood cholesterol in monkeys using gene editing

Medical

Gene editing successfully lowers monkey cholesterol levels

In one of the first examples of gene-editing technology being effectively used to knock out the expression of a gene in non-human primates, researchers have lowered the blood cholesterol in monkeys by disabling a single gene in the liver.

Amyloid beta clusters (in red) have been found to accumulate faster in the presence of cholesterol in brain cell membranes

Medical

How cholesterol in the brain may accelerate the onset of Alzheimer’s disease

A landmark study has revealed that cholesterol in the brain may play a fundamental role in catalyzing the formation of amyloid beta clusters, thought to be a central mechanism leading to the devastating degenerative symptoms of Alzheimer’s disease.

A new gene-silencing drug gives hope of a future where keeping LDL cholesterol levels low is as simple as a small injection from your GP once or twice a year

Medical

Gene-silencing drug halves cholesterol levels with a single jab

A new gene-silencing drug that can lower cholesterol levels is proving promising in its initial clinical test results. The treatment was shown to reduce the levels of low-density lipoprotein (LDL) cholesterol in patients' blood by up to 51 percent in the month following one single treatment.

In a mouse study, red cabbage microgreens helped lower “bad” cholesterol, weight gain and blood pressure in animals on a high fat diet

Health & Wellbeing

Mouse study suggests microgreens could offer macro benefits

When a “health food” trend hits the tables, it's hard not to feel a little cynical. But a new animal study by US Department of Agriculture researchers suggests that red cabbage microgreens, now popular in restaurants and on cooking shows, offers a way to reduce weight gain and high blood pressure.

A new therapy is making it possible for people with high cholesterol to reduce their levels to those of a newborn baby, and increase their quality of life

Biology

"Newborn" cholesterol levels shown to slash cardiovascular threat

We all know that lowering "bad” cholesterol levels can help reduce our risk of heart disease. But is there any benefit to having very low levels of cholesterol? According to new research, the answer is a resounding "yes."

Researchers were able to lower cholesterol levels in animals using a new vaccine that targets a protein called PCSK9

Health & Wellbeing

Vaccine shows promise as cheap, effective treatment for prevention of high cholesterol

Researchers have developed a cheap vaccine that reduces cholesterol levels in animals, suggesting a cheap and effective way to prevent dangerously high levels in humans mightn't be so far away.