Cholesterol

A phase 2 clinical trial of a cholesterol-reducing drug called evinacumab has reported promising results. In patients with extremely high cholesterol, the drug was able to reduce levels by about half, compared to a placebo.

Using a multi-modal approach to data analysis, scientists have identified a subtype of autism linked with a gene cluster known to affect neurodevelopment and lipid metabolism. It's suggested this subtype accounts for nearly seven percent of autism cases.

Scientists have discovered a new mechanism by which a “bad” type of cholesterol gains entry to the cells, offering new targets for drugs that could lower its levels in the blood to help prevent disease.

A new study, led by researchers at the Broad Institute of MIT and Harvard, is shedding light on a century-old mystery. The study describes how bacteria in the gut can metabolize cholesterol at levels high enough to improve a person’s cardiac health.

A new study has delved into the impact of gut bacteria on cholesterol levels, detailing the "remarkable effects" of the introduction of a set of molecules that shift the balance of bacterial species in a way that prevents thickening of the arteries.

Statin drugs are commonly taken to help manage cholesterol levels. But now, researchers at Johns Hopkins Medicine have found that they may also kill some cancer cells by starving them of nutrients, and uncovered the mechanism for how that can happen.

A study is suggesting alterations to a dairy cow’s diet can result in milk lower in saturated fat and a clinical trial in humans demonstrates these natural “healthier” dairy products may lead to positive heart health effects.

An entirely new cholesterol-lowering drug is on track for broad clinical approval after the latest trial results to be published reveal it is both safe and effective when administered in conjunction with commonly prescribed statins.

In one of the first examples of gene-editing technology being effectively used to knock out the expression of a gene in non-human primates, researchers have lowered the blood cholesterol in monkeys by disabling a single gene in the liver.

A landmark study has revealed that cholesterol in the brain may play a fundamental role in catalyzing the formation of amyloid beta clusters, thought to be a central mechanism leading to the devastating degenerative symptoms of Alzheimer’s disease.

A new gene-silencing drug that can lower cholesterol levels is proving promising in its initial clinical test results. The treatment was shown to reduce the levels of low-density lipoprotein (LDL) cholesterol in patients' blood by up to 51 percent in the month following one single treatment.

When a “health food” trend hits the tables, it's hard not to feel a little cynical. But a new animal study by US Department of Agriculture researchers suggests that red cabbage microgreens, now popular in restaurants and on cooking shows, offers a way to reduce weight gain and high blood pressure.