Drug delivery
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Melbourne’s Monash University has commenced a Phase 1 clinical trial to test a novel inhaled powder designed to prevent postpartum hemorrhage, a serious complication of childbirth that causes tens of thousands of deaths worldwide.
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MIT scientists have developed a new wearable patch that can deliver drugs through the skin more efficiently and painlessly. The device uses pulses of ultrasound to pry open the skin, which could improve topical medications or even tattoos.
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Unfortunately for us, harmful bacteria is incredibly good at adapting to survive. But a team of scientists believes it has the key to killing bugs that resist traditional antibiotics, with an adaptive drug inspired by a military tank.
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Missing medications or not taking them as required can have costly results. Bioengineers at Rice University may have the solution to missed medications, using advanced technology to create a system that delivers time-released drugs.
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Wouldn't it be nice if medication could be injected without using a painful needle, and if that medication could be stored at room temperature? Well, it turns out that MOF-Jet technology may make both things possible.
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While there are already a variety of implants that dispense medication within the body, most of them either can't be externally controlled, or they eventually have to be surgically removed. A new one, however, uses light to avoid both problems.
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High cholesterol levels are a common and potentially deadly health problem, but a new drug could help more people manage the condition. An experimental pill has been shown to reduce levels of “bad” cholesterol by 60% in a phase 2 clinical trial.
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Scientists at MIT have developed bottlebrush-shaped molecules that can carry groups of different cancer drugs in just the right ratios. Tests in mice showed significantly improved outcomes compared to just giving the drugs loose.
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In an ideal world, managing diabetes wouldn’t involve insulin injections but just popping a pill. Now a team of scientists has demonstrated an oral tablet that’s self-propelled by chemical “micromotors” to deliver insulin in the colon of rats.
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Scientists have found a way to fight cancer with cancer, by genetically engineering cancer cells to release drugs at established tumor sites and stimulating the immune system. Tests in mice showed promise as both a therapy and preventative vaccine.
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While islet cell transplants allow some diabetics to forgo daily insulin injections, those people must take immunosuppressive drugs to protect those cells. A new implant, however, could administer the drugs for them, with fewer side effects.
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Researchers have developed an implantable pump that can deliver chemotherapy drugs directly into the brain to fight hard-to-treat cancer. In a phase 1b trial, patients were able to undergo the therapy while going about their day-to-day activities.
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