gene therapy
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They weigh about an ounce, spend their lives underground and are unlikely to be shortlisted for any cute animal calendars, but the fascinating naked mole-rat continues to offer clues that it holds the key to anti-aging under its pale, wrinkly skin.
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A third of the US population lives with chronic pain. While the economic burden is well known, it also has a huge impact on mental health, opioid misuse and quality of life. Scientists now say they know the genetic hack to cut off the pain entirely.
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Humans have done remarkably well in evolutionary terms, but one design flaw has to be our inability to replace lost teeth throughout our lives. Now, scientists believe they have the antibody treatment to do just that, and it could be available by 2030.
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A new study led by scientists at Harvard Medical School has identified chemical cocktails that can restore cells to a more youthful state, paving the way for aging reversal treatments that are more accessible than gene therapy.
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Yale scientists have discovered a new potential treatment avenue to fight cancer. Using CRISPR gene-editing, the team eliminated extra chromosomes from cancer cells and found that they could no longer grow out of control.
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CRISPR-Cas9 is the household name of genetic engineering tools, but there might be other, better ways. MIT scientists have now demonstrated an alternative called Fanzor, which is naturally found in animals so could be a better fit for human use.
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As a way of treating hemophilia, researchers have, for the first time, delivered gene therapy directly into the livers of baboons without using a viral carrier. The study shows it is safe and effective and may lead to a new treatment for the disease.
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Getting your cat spayed is a normal part of pet ownership, but it can be expensive, invasive and not very practical on strays. Now scientists have tested a new method that renders female cats permanently sterile with a single gene therapy injection.
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Age-related hearing loss impacts one in three adults aged 64 to 75 in the US, and around half of these cases are down to faulty genes. Using older animals to mirror a human study, scientists successfully reversed hearing loss caused by one such gene.
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A new technique may one day help restore sight to patients with inherited vision impairment. The regenerative therapy works by expressing genes that convert dormant cells into new light-sensing cells in the retina to replace those lost to disease.
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Researchers have developed a highly efficient new gene-editing method that uses virus-based protein fragments. The method could be used to level up existing cell and gene therapies used to treat cancer and other diseases.
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The high eye pressure seen in glaucoma slowly leads to blindness. For some, treatment with eye drops doesn’t work. Researchers have used gene therapy to develop a promising new way of treating the high eye pressure associated with glaucoma.
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