Genetic engineering

While you might think that it's best to keep crops fungus-free, there are some fungi that actually help plants grow. In order to observe that relationship, scientists have created plants with roots that turn red when infiltrated by beneficial fungi.

Food security is a major potential problem, especially in the face of climate change. New research has shown that manipulating RNA in plants can drastically boost the amount of food they produce, and make them more resistant to drought conditions.

Sugarcane is a key food crop, but its large environmental impact leaves plenty of room for improvement. Unfortunately it’s tricky and time-consuming to breed new varieties, but now researchers have used CRISPR gene-editing to do so more easily.

The CRISPR gene-editing tool has been successfully used in space for the first time. Researchers onboard the International Space Station have edited colonies of yeast to study how they repair DNA damage, which could one day help protect astronauts.

Japanese researchers have developed a new type of cholera vaccine by genetically modifying rice to carry a non-toxic cholera antigen. The vaccine needs no refrigeration with the rice simply ground into a powder, mixed with water and consumed.

New clinical data shows that CRISPR gene editing can be done safely and effectively inside the body. CRISPR was injected into the bloodstream of patients with a genetic disease, with better outcomes than current treatments and no side effects.

One of the challenges of farming lies in the fact that by the time plants appear to be stressed, it may already be too late to address the problem. A new potato, however, is designed to warn farmers by fluorescing at the earliest stages of stress.

Scientists at Harvard have demonstrated an alternative to CRISPR – a genetic engineering system called Retron Library Recombineering (RLR) that works without cutting DNA and can be quickly applied to huge populations of cells.

In a breakthrough new study, scientists have created human-monkey chimera embryos for the first time. They make for more accurate models of human biology and disease - but of course they also raise some complicated ethical concerns.

Scientists at the Salk Institute hope to tackle climate change and food security by unraveling the genomic architecture behind various plant species, and have gleaned some valuable new lessons from the fastest-growing example we know of.

A gene known as Myc is linked to cancer growth, but has long been considered “undruggable." Now, researchers at Vanderbilt University have found a way to bypass it and shut down a protein that it interacts with, shrinking tumors in a matter of days.

One of the most promising emerging cancer therapies is CAR T cell immunotherapy, where a patient’s own immune cells are supercharged to fight tumors. Now researchers have found a way to refresh exhausted immune cells and get them back into battle.