Genetic engineering

A new technique has been added to the CRISPR gene-editing toolbox. Known as PASTE, the system uses virus enzymes to “drag-and-drop” large sections of DNA into a genome, which could help treat a range of genetic diseases.

Although plain popcorn is a relatively healthy snack, it's still not one that most people would think of as being very nutritious. That could change, however, as a new variety reportedly offers nearly twice the normal levels of an important nutrient.

With demand for vegetable oil only expected to increase, a team of scientists in Singapore has demonstrated a way of increasing the yield of oil from plants through genetic engineering, which could increase the output by as much as 18%.

Scientists have demonstrated a new potential way to edit the genomes of bacteria in complex environments, by equipping viruses to hunt them down and insert the CRISPR gene-editing system.

While plants such as soybeans are major sources of biofuel, they're grown on land that could otherwise be used for food crops. With that problem in mind, scientists have genetically engineered oil-producing duckweed that could be grown in wastewater.

When it comes to keeping mosquitoes from spreading malaria, some approaches involve killing the insects, or stopping them from acquiring malaria parasites. A new method, however, stunts the growth of the parasites once they're in the mosquito's gut.

After more than a decade of development a nutritionally enhanced purple tomato has been deemed safe to grow by the USDA. The tomatoes have been gene edited to produce 10 times more antioxidants than pre-existing varieties.

It takes tons of plant matter to make each gram of the cancer drug vinblastine. To find an alternative source, scientists have engineered yeast to produce the precursors of vinblastine, which could help make this vital drug more available and affordable.

Colossal has plans to resurrect the mammoth, and now it's revealed the second species on its de-extinction list – Australia’s lost thylacine. Partnering with a University of Melbourne lab, the project could revive the creature in about a decade.

Scientists have demonstrated an intriguing new variation on the CRISPR gene-editing system, which involves fixing a mutation on one chromosome by copying a healthy version from the other. “Nicking” the DNA also seemed to work better than cutting it.

As important as CRISPR-Cas9 gene-editing is, it has a relatively high error rate, which can introduce potentially harmful mutations. German researchers have now developed a more refined tool that reduces errors by nicking DNA instead of cutting it.

Researchers at the University of Maryland have developed a new gene-editing system they call CRISPR-Combo, which can edit multiple genes at once while also changing the expression of others in plants, to increase efficiency of genetic engineering.