Immunotherapy

Hugely promising cancer immunotherapy drug dostarlimab is one step closer to being widely available, after the Food and Drug Administration granted it Breakthrough Therapy Designation status that, if successful, will expedite its path to market.

A new kind of cancer gene therapy can be remotely activated at a specific part of the body. The team developed a version of CRISPR that responds to ultrasound, and demonstrated how it can be used to clear cancer in mice.

Scarring of heart tissue can be slowed but not stopped, and can lead to heart failure. But a new study has shown that an existing immunotherapy could stop scar tissue formation after heart attacks.

Global healthcare company Grifols has partnered with BARDA, the Biomedical Advanced Research and Development Authority, to develop the first immune therapy eye drops to prevent the long-term effects of exposure to sulfur mustard, commonly called ‘mustard gas.’

T cells are our first line of defense against cancer, but the battle tends to exhaust them. Now, scientists have found a way to give them extra “batteries” to keep them fighting longer, with promising early results in mice.

A 67-year-old London man with lung cancer is the first to receive a new cancer vaccine as part of an international trial. The early-stage research will test the immune therapy’s safety and whether it can be used together with existing cancer treatments.

One dose of a new treatment, delivered by nasal spray, clears away build-ups of the toxic tau protein associated with Alzheimer’s disease from inside brain cells, improving memory, according to new research. It paves the way for new treatments for the debilitating disease.

For the first time, scientists have successfully created a mouse with a 100% functional human immune system and microbiome. This 'humanized' mouse takes the guesswork out of research and may revolutionize how we test new drugs and understand diseases.

The US Food and Drug Administration (FDA) has green-lit the fast-tracking of an innovative personalized treatment for advanced prostate cancer following a promising clinical trial where the cancer disappeared completely in almost 40% of participants.

Aspirin, taken by around 29 million Americans daily, has increasingly been linked to inhibiting the growth of certain cancers – but we didn't quite know how. Now, scientists have uncovered how it helps the immune system see and kill cancer cells.

Giving infliximab, an immunotherapy drug, as soon as possible after diagnosis with Crohn’s disease significantly reduced complications, including the need for urgent surgery by a factor of 10, a clinical study has found.

A new form of immunotherapy helps immune cells “armor” themselves against exhaustion by releasing their own medicine to keep them going in the fight against cancer. The new method is faster and cheaper to produce than existing immunotherapies.