Immunotherapy
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One dose of a new treatment, delivered by nasal spray, clears away build-ups of the toxic tau protein associated with Alzheimer’s disease from inside brain cells, improving memory, according to new research. It paves the way for new treatments for the debilitating disease.
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For the first time, scientists have successfully created a mouse with a 100% functional human immune system and microbiome. This 'humanized' mouse takes the guesswork out of research and may revolutionize how we test new drugs and understand diseases.
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The US Food and Drug Administration (FDA) has green-lit the fast-tracking of an innovative personalized treatment for advanced prostate cancer following a promising clinical trial where the cancer disappeared completely in almost 40% of participants.
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Aspirin, taken by around 29 million Americans daily, has increasingly been linked to inhibiting the growth of certain cancers – but we didn't quite know how. Now, scientists have uncovered how it helps the immune system see and kill cancer cells.
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Giving infliximab, an immunotherapy drug, as soon as possible after diagnosis with Crohn’s disease significantly reduced complications, including the need for urgent surgery by a factor of 10, a clinical study has found.
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A new form of immunotherapy helps immune cells “armor” themselves against exhaustion by releasing their own medicine to keep them going in the fight against cancer. The new method is faster and cheaper to produce than existing immunotherapies.
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Researchers have found adding a hyperactive form of the protein Rac2 to macrophages, immune cells that eat pathogens, causes them to cannibalize T cells. The novel technique could potentially boost the effectiveness of an emerging cancer treatment.
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Researchers have harnessed the cancer-destroying abilities of the body’s natural killer cells. Nanodrones selectively target a tumor, enabling the killer cells suppress cancer growth, opening the door to novel, cancer-specific immunotherapies.
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Moderna has announced results of a Phase 2b trial of its mRNA treatment for skin cancer. When paired with immunotherapy, the treatment significantly reduced risks of recurrence, metastasis and death, paving the way for trials against other cancers.
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In what has already been tagged as a “game-changer” for cancer treatment, the potent once-a-day tablet known as divarasib has continued to impress at Phase 1b trial stage, outperforming not just current therapies but its previous trial results.
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A study has found that a fatty acid found in meat and dairy may boost the cancer-killing abilities of the immune system’s T cells. Also found to enhance the effectiveness of immunotherapy, the nutrient could be used to complement cancer treatments.
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A Phase 2 clinical trial of immunotherapy drug tarlatamab, produced promising results in patients with small cell lung cancer, a particularly aggressive form of cancer, for whom previous treatments haven't worked.
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