Immunotherapy

Australian researchers have affirmed an unusual, almost paradoxical, observation that cancer patients with high body mass index tend to display greater survival rates than patients with average healthy weights.

Cancer has a knack for deceiving the immune system, giving itself time to grow and spread. Now, researchers at QIMR Berghofer Medical Research Institute have identified one way it does so, and found a method to counter it in mouse tests.

One of the most promising types of cancer treatment involves boosting the immune system’s response to the presence of cancer, and now two new mouse studies out of Yale University are reporting breakthroughs in this area.

A new study is suggesting a simple breath analysis can accurately predict whether lung cancer patients will positively respond to immunotherapy treatments.

The first oral immunotherapy agent to treat peanut allergy is set to be approved, but questions still remain over how effective and long-lasting it is.

A study from Imperial College London is suggesting antibiotic use prior to cancer immunotherapy can significantly reduce the efficacy of the treatment.

Cancer cells often deploy specific “don't eat me” signals to hide from immune cells. A breakthrough new study has homed in on a previously undiscovered signalling protein that, if effectively inhibited, may lead to new treatments for breast, ovarian, and other difficult-to-treat cancers.

There exists a group of HIV-positive people who have a rare ability to naturally control the HIV infection. Now, after years of research, a team of scientists from the Institut Pasteur in Paris, has successfully reprogrammed cells that lack this ability, giving them the same, antiviral potency.

CAR-T cell therapy involves reprogramming T-cells to hunt down cancer, which has been effective against blood cancers but not so much against solid tumors. Now, scientists at MIT have found a way to supercharge the technique with a vaccine booster.

​Immunotherapy is a form of cancer treatment that seeks to supercharge the body’s natural immune defenses, but pancreatic cancer is one that has so far been able to evade its advances. Scientists are now reporting a discovery that might help the immune system regain the upper hand.

Cytokines are small proteins that could help fight cancer, but they're toxic to healthy cells. Now, researchers from MIT have managed to keep cytokines contained in cancer cells, attaching them with proteins that stick like Velcro.

A meta-analysis of a dozen trials into the efficacy of an oral immunotherapy treatment designed to reduce allergic reactions to peanuts has concluded the treatment may work in clinical environments but it also results in patients suffering from more real-world adverse allergic events.