Massachusetts General Hospital

An experimental drug has been shown to slow the progression and prolong survival of patients suffering from the neurodegenerative disease ALS. With Phase 2 human trials complete, the company developing the treatment is working to accelerate its approval.

A team of researchers from Massachusetts General Hospital, trawling through hospital admission data, may have found a simple blood-based biomarker that can help doctors assess those patients most at risk of suffering the worst effects of COVID-19.

HIV is an insidious virus, hibernating inside cells ready to re-emerge if treatment is stopped. Now a team of researchers has found a way to shrink that viral reservoir by adapting a cancer immunotherapy technique to supercharge immune cells in mice.

The results of the largest clinical trial ever conducted into the relationship between vitamin D and depression suggest the vitamin does not improve mood or prevent depression. The trial did not investigate subjects with pre-existing vitamin D deficiencies.

Two new studies, published in The Lancet Neurology, are suggesting increasing levels of a particular brain protein, detected in blood and spinal fluid, could be the earliest sign of neurodegenerative diseases such as Alzheimer’s and Huntington’s.

A new mouse study from Massachusetts General Hospital has for the first time established a connection between elevated levels of calcium in mitochondria and neuron death associated with Alzheimer's disease.

It sure sounds like an online pop-up ad, but Harvard scientists have created and tested a new treatment that melts away body fat. The new technique involves injecting an icy saline solution directly into fat deposits to shrink them by half.

A leading suspect in the onset of Alzheimer's disease is a toxic plaque called amyloid-beta, which new research has found could be better cleared away by harnessing natural oscillations in the blood vessels known as vasomotion.

When someone has a severe burn, a protective covering needs to be temporarily grafted onto the wound site. Although that covering typically consists of skin from a human cadaver, live-cell pig skin has now been used on a patient for the first time.

Freezing is one of the simplest methods of preserving food, biological tissue and other perishables, but the formation of ice crystals can damage cells. Now, researchers have developed a new way to “supercool” water in a liquid form well below the usual freezing point.

​Although high-voltage electrical shocks can cause burns, scientists have recently shown that the application of pulsed electric fields actually aids in healing them. It does so by killing skin cells.

Scientists are working on ways to create bioengineered human hearts by first stripping donor hearts of cells and then using the potential recipient's own induced pluripotent stem cells to generate cardiac muscle cells that can be used to repopulate the heart in an automated bioreactor system.