Microbiome

A first-of-its-kind clinical trial has found fecal transplants may be helpful reducing drinking behaviors in those suffering severe alcohol use disorder. The study points to a compelling relationship between the gut microbiome and addiction disorders.

Researchers from Ohio State University have created the first catalog of viral populations known to inhabit the human gut. Called the Gut Virome Database, the study suggests each person’s gut viral population is as unique as their fingerprints.

The bacteria that are present in a person's gastrointestinal tract can reveal a lot about their health. A newly developed capsule could provide even more information, by gathering bacteria from specific locations within that tract.

New research is describing how certain species of gut bacteria can enhance the efficacy of cancer immunotherapy. The animal study offers insights into a metabolite-immune pathway that could lead to microbial therapies incorporated into immunotherapy treatments.

New research suggests a high-fat diet and antibiotics work together to promote a gut microbiome imbalance that can lead to bowel inflammation. The study sheds light on the causal mechanism by which environmental factors can trigger IBD.

Researchers have for the first time studied the gut microbiome of subjects with prediabetes, revealing a person’s unique gut bacteria population could be used to predict their likelihood of developing type 2 diabetes.

New research from the University of Colorado Boulder has offered some of the clearest evidence to date showing how the gut microbiome produces a metabolite that, over time, contributes to age-related declines in cardiovascular health.

New research from the University of Massachusetts Amherst is adding weight to a growing body of evidence suggesting the food additive titanium dioxide, also known as E171, can disrupt the gut microbiome, leading to colonic inflammation.

Two new studies are offering strong evidence that bowel inflammation and obesity are risk factors for developing dementia. The studies are observational, and cannot determine causality, but they build on prior research reaching similar conclusions.

A new study, led by researchers at the Broad Institute of MIT and Harvard, is shedding light on a century-old mystery. The study describes how bacteria in the gut can metabolize cholesterol at levels high enough to improve a person’s cardiac health.

Building on the growing link between poor oral health and gastrointestinal disease, research from the University of Michigan has homed in on the possible mechanisms by which periodontitis can exacerbate the gut inflammation seen in patients with IBD.

A new study has delved into the impact of gut bacteria on cholesterol levels, detailing the "remarkable effects" of the introduction of a set of molecules that shift the balance of bacterial species in a way that prevents thickening of the arteries.