Obesity

The next transformative phase of weight-loss medication is upon us, with the US Food and Drug Administration (FDA) approving Novo Nordisk's highly anticipated oral GLP-1 drug – with a starting dose available in early January for US$149.

Researchers have homed in on a single gut microbe that acts to prevent fat gain, even with a high-fat diet. The discovery adds to the booming science of finding ways to enlist the microbes that already live in our bodies to help us improve our health.

A massive global study has turned up some grim news: That 87% of us are not routinely getting quality sleep and meeting physical activity levels needed for long-term health. And, scientists discover, one is more influential than the other.

The World Health Organization has finally made its recommendations on using GLP-1 therapeutics for weight loss, though it remains to be seen whether it changes their status for prescribing or price. And scientists still have some concerns.

Scientists have made a major breakthrough in understanding how fat cells grow in size, in response to accommodating larger droplets of fat. The findings unlock a new path in tackling obesity, by reducing the amount of fat our cells can store away.

In the most comprehensive investigation of the ketogenic diet’s mental health effects yet, researchers pooled 50 studies spanning six decades to see what we actually know about its influence on mood. The results are a mix of promising and uncertain.

Some people don’t lose enough weight after bariatric surgery, but a new study shows that adding a daily shot of GLP-1 drug liraglutide can help patients shed extra pounds and may reduce the need for further surgery.

A blend of natural compounds that blocks sugar damage extended lifespan in mice by curbing hunger and improving metabolism in a new study. It hints at a new way to fight obesity, diabetes, and aging without cutting calories.

A new class of weight-loss drug has shown it can significantly boost weight loss when paired with GLP-1 therapy – without adding side effects – in a mid-stage clinical trial, pointing to a powerful new combination approach to tackling obesity.

Compounds in green tea can reprogram muscle metabolism to boost insulin sensitivity and glucose tolerance, according to new findings that further our understanding of why this ancient drink has long been linked to protect against obesity.

We've known for some time that obesity affects the brain, but now scientists have found that it's where you carry it that matters most. Deep visceral fat around organs has the biggest impact on brain aging, affecting a suite of cognitive functions.

A headline-grabbing study on apple cider vinegar has been pulled from the record, striking a blow to the science and wellness worlds. The research, which claimed that the tonic triggered massive weight loss, was found to be riddled with errors.