Obesity

It looks like we'll see oral GLP-1 drugs on the market by 2026, with Eli Lilly reporting impressive results from a large, robust 72-week trial that saw obese patients lose an average of 27.3 lb, or 12.4% of their body weight, with a once-daily pill.

Byproducts from gut bacteria breaking down tryptophan, a dietary amino acid, can restore hormone-secreting gut cells reduced by obesity, a new study found. It opens the door to a natural, side-effect-free alternative to GLP-1 drugs like Ozempic.

While obesity significantly increases the risk of many cancers, scientists have now uncovered that there are specific dietary fat drivers that impede the body's ability to fight tumors. This landmark reveals that not all fats are created equal.

In a landmark 14-year study, researchers found that artificially sweetened drinks raise the risk of developing type 2 diabetes by more than a third, higher than those with sugar. It challenges the perception that diet drinks are healthier options.

The US Food and Drug Administration has instructed all GLP-1 drug-makers to update warning labels to include the risk of serious kidney injury that can result from dehydration. This comes after cases of acute kidney injury have required hemodialysis.

The first human-tested weight-loss drug that burns calories through creatine-based heat generation, without reducing appetite, has successfully completed its Phase I trial. In the trial, participants lost an average of 3% fat mass in two weeks.

For decades now, obesity has been defined by a number on a scale or where you land on the body mass index measure. But a groundbreaking study has found that it’s far more complex, finding 11 distinct biological types, each with their own health risks.

What if you could inject a drug into a "problem area" – like the abdomen – and have it safely and rapidly kill off fat cells? We could be within 12 months of this reality, as the world's first safe, targeted fat-loss jab enters Phase 3 trials.

For the first time, scientists have uncovered a distinct biological process triggered in those who suffer from high levels of Monday anxiety, resulting in chronic stress. And it can lead to serious health problems if it's left unmanaged.

Synching your daily calories with your own circadian rhythm can improve glucose metabolism, protecting against type 2 diabetes and obesity. A new study uncovers the relationship between metabolic health and our personal, inherent biological clock.

Cutting a single amino acid from the diet caused rapid, drastic weight loss in mice by converting white fat into calorie-burning brown fat. The study reveals a powerful new mechanism for weight loss that doesn’t rely on eating less and moving more.

A new study reveals that Americans are confused about what “processed food” actually means, and which types pose health risks. Researchers found major gaps between public perception and science, highlighting the need for more comprehensive education.