Pain

A new proof-of-concept study suggests CRISPR gene therapy may be a promising alternative to opioids for chronic pain. The preliminary investigation demonstrated lowered pain sensitivity in mice after temporarily repressing activity of a specific gene.

New research suggests cannabis use can be linked to higher rates of "rebound headaches" in migraine sufferers. The research is observational and retrospective, but it is yet another finding questioning how helpful cannabis is for chronic migraine patients.

Given the difficulty in diagnosing the Alzheimer's, scientists are exploring all kinds of avenues to reveal the disease in its early stages. New research indicates a person's pain perception could be used a biomarker for diagnosing Alzheimer's.

New research led by scientists from UT Southwestern suggests a novel combination of three old antibiotics may be repurposed into an alternative to opiates for a particular kind of nerve pain.

In order to keep patients from developing opioid addictions, it's best if doctors can avoid prescribing the things in the first place. A new surgical patch could help, by gradually releasing painkillers right where they're needed.

A new study has found integrating an immersive virtual reality system into a chronic pain treatment can significantly enhance a patient’s pain-relief outcome. The research suggests “digiceutical” therapies may be effective for patients suffering chronic pain.

A new understanding of the way tarantula toxins shut down electrical signals in the spider’s prey has given scientists hope of recreating this effect, but in a positive way through advanced drugs that treat chronic pain.

A novel technique that involves directing low-grade radiofrequency energy through sensory nerves is shaping as a promising treatment for arthritis, after delivering significant and long-lasting decreases in pain in an early study.

Spider venom isn’t normally something you want in your body, but there might be exceptions. Australian researchers have identified two peptides from tarantula venom that show promise in blocking organ pain, working particularly well in mice with IBS.

Australian researchers have solved the mystery behind the sting of one of the most venomous plants on the planet. The newly discovered neurotoxin explains how Australian stinging trees cause pain that can last for extraordinarily long periods.

Researchers in Australia have succeeded in developing an artificial skin that responds to painful stimuli, heat and pressure like real skin does, which they see as an important step towards intelligent machines and prosthetics.

An incredible, first-of-its-kind trial testing the pain-killing properties of LSD microdoses has delivered the compelling suggestion that tiny, non-psychedelic doses of this infamous drug could serve as an effective analgesic.