Regenerative Medicine
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Adding rat stem cells to a mouse embryo resulted in a ‘hybrid brain’ in which the rat cells stepped in to restore function when the mouse’s sense of smell was removed. The new research represents a step forward in regenerative medicine.
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California-based biopharmaceutical company Rubedo Life Sciences has announced that thanks to US$40 million in financial backing, it can commence human trials of its drug RLS-1469, designed to target the senescent cells that cause age-related disease.
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A component of the aromatic spice cinnamon has encouraged hair follicles to sprout in the lab, and now researchers have set their sights on using it to develop a novel treatment that could reverse hair loss through the use of natural compounds.
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A clinical trial will soon commence investigating whether nose cartilage can be used to regenerate knee joints that have been severely worn down by osteoarthritis. If successful, the procedure could be an alternative treatment for the condition.
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Researchers at TU Wien have developed a new way to grow cartilage from stem cells and guide it into basically any shape required. The breakthrough could lead to better ways to patch up injuries.
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Researchers have successfully regenerated functional bladder tissue in a baboon using the animal’s own bone marrow cells. The findings open the door to a novel treatment for severe bladder dysfunction for which treatment is currently limited.
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The most comprehensive genetic map of oral stem cells to date has provided new insight into their specialized development pathways and opens the door to targeted regenerative medicine and interventions, such as therapies to grow or repair bone.
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Researchers have used FDA-approved cancer drugs to regenerate pancreatic cells damaged by diabetes into cells that secrete insulin in response to glucose. The discovery could mean that one day, diabetics can avoid multiple daily insulin injections.
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Heart tissue normally can't regenerate after an injury. But now, scientists at Max Planck have shown in mice that reprogramming the energy metabolism of the heart allows it to regenerate after a heart attack, which could open new therapies.
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A complete spinal cord injury results, tragically, in total paralysis of all limbs and muscles below the injury site. But now, scientists at EPFL have demonstrated in mice a new gene therapy that can regenerate nerves and restore the ability to walk.
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A new stem cell therapy for Parkinson’s disease, in which the donor would also become the transplant recipient, is one step closer to human trials after scientists were able to successfully grow and rebuild neurons in an animal model.
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A new technique may one day help restore sight to patients with inherited vision impairment. The regenerative therapy works by expressing genes that convert dormant cells into new light-sensing cells in the retina to replace those lost to disease.
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